Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma
A twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound revealed a peritoneal mass of unclear origin. Transfusio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-06-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/6/2/55 |
| _version_ | 1818453622540730368 |
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| author | Masashi Yuki Eiji Naitoh |
| author_facet | Masashi Yuki Eiji Naitoh |
| author_sort | Masashi Yuki |
| collection | DOAJ |
| description | A twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound revealed a peritoneal mass of unclear origin. Transfusion, followed by mass resection, rapidly resolved the anemia without further immunosuppressive treatment. Histopathology confirmed extraluminal jejunal leiomyosarcoma. Multiple mechanisms, including immune-mediated destruction, likely contributed to the anemia. To the authors’ knowledge, this is the first report that describes the resolution of immune-mediated hemolysis in a dog after the removal of an intestinal neoplasm. |
| first_indexed | 2024-12-14T21:41:55Z |
| format | Article |
| id | doaj.art-4ebc6fca14e04f45adf7f8a5c587c113 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-12-14T21:41:55Z |
| publishDate | 2019-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-4ebc6fca14e04f45adf7f8a5c587c1132022-12-21T22:46:27ZengMDPI AGVeterinary Sciences2306-73812019-06-01625510.3390/vetsci6020055vetsci6020055Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal LeiomyosarcomaMasashi Yuki0Eiji Naitoh1Yuki Animal Hospital, 2-99 Kiba-cho, Minato-ku, Aichi 4550021, JapanYuki Animal Hospital, 2-99 Kiba-cho, Minato-ku, Aichi 4550021, JapanA twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound revealed a peritoneal mass of unclear origin. Transfusion, followed by mass resection, rapidly resolved the anemia without further immunosuppressive treatment. Histopathology confirmed extraluminal jejunal leiomyosarcoma. Multiple mechanisms, including immune-mediated destruction, likely contributed to the anemia. To the authors’ knowledge, this is the first report that describes the resolution of immune-mediated hemolysis in a dog after the removal of an intestinal neoplasm.https://www.mdpi.com/2306-7381/6/2/55dogimmune-mediated hemolytic anemialeiomyosarcoma |
| spellingShingle | Masashi Yuki Eiji Naitoh Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma Veterinary Sciences dog immune-mediated hemolytic anemia leiomyosarcoma |
| title | Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma |
| title_full | Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma |
| title_fullStr | Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma |
| title_full_unstemmed | Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma |
| title_short | Complete Remission of Associative Immune-Mediated Hemolytic Anemia in a Dog Following Surgical Resection of Intestinal Leiomyosarcoma |
| title_sort | complete remission of associative immune mediated hemolytic anemia in a dog following surgical resection of intestinal leiomyosarcoma |
| topic | dog immune-mediated hemolytic anemia leiomyosarcoma |
| url | https://www.mdpi.com/2306-7381/6/2/55 |
| work_keys_str_mv | AT masashiyuki completeremissionofassociativeimmunemediatedhemolyticanemiainadogfollowingsurgicalresectionofintestinalleiomyosarcoma AT eijinaitoh completeremissionofassociativeimmunemediatedhemolyticanemiainadogfollowingsurgicalresectionofintestinalleiomyosarcoma |