Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

Regulation of TRPML1 channel activity and inflammatory exosome release by endogenously produced reactive oxygen species in mouse podocytes

The nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome in podocytes has been implicated in the initiation of glomerular inflammation during hyperhomocysteinemia (hHcy). However, the mechanism by which NLRP3 inflammasome products are released from p...

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Detalles Bibliográficos
Main Authors: Guangbi Li, Dandan Huang, Ningjun Li, Joseph K. Ritter, Pin-Lan Li
Formato: Artigo
Idioma:English
Publicado: Elsevier 2021-07-01
Series:Redox Biology
Subjects:
Podocyte
Homocysteine
Reactive oxygen species
TRPML1 channel
Exosome
Lysosome
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2213231721001713

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