Integrating extracellular vesicle and circulating cell‐free DNA analysis using a single plasma aliquot improves the detection of HER2 positivity in breast cancer patients

Integrating extracellular vesicle and circulating cell‐free DNA analysis using a single plasma aliquot improves the detection of HER2 positivity in breast cancer patients

Abstract Multi‐analyte liquid biopsies represent an emerging opportunity for non‐invasive cancer assessment. We developed ONCE (One Aliquot for Circulating Elements), an approach for the isolation of extracellular vesicles (EV) and cell‐free DNA (cfDNA) from a single aliquot of blood. We assessed ON...

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Bibliographic Details
Main Authors: Vera Mugoni, Yari Ciani, Orsetta Quaini, Simone Tomasini, Michela Notarangelo, Federico Vannuccini, Alessia Marinelli, Elena Leonardi, Stefano Pontalti, Angela Martinelli, Daniele Rossetto, Isabella Pesce, Sheref S. Mansy, Mattia Barbareschi, Antonella Ferro, Orazio Caffo, Gerhardt Attard, Dolores Di Vizio, Vito Giuseppe D'Agostino, Caterina Nardella, Francesca Demichelis
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Journal of Extracellular Biology
Subjects:
breast cancer
cell‐free DNA (cfDNA)
ddPCR
EV‐RNA
extracellular vesicles (EV)
HER2
Online Access:https://doi.org/10.1002/jex2.108

Internet

https://doi.org/10.1002/jex2.108

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