FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells
The inhibitory effect of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters DAP12 and FcεRI γ-chain (FcRγ) has been found in many immune functions. Herein, we have further explored the role of these adapters in C-type lectin receptors response. We identified that FcRγ, but not...
Main Authors: | Yi-Gen Pan, Yen-Ling Yu, Chi-Chien Lin, Lewis L. Lanier, Ching-Liang Chu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-10-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.01424/full |
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