The structure of the core NuRD repression complex provides insights into its interaction with chromatin
The NuRD complex is a multi-protein transcriptional corepressor that couples histone deacetylase and ATP-dependent chromatin remodelling activities. The complex regulates the higher-order structure of chromatin, and has important roles in the regulation of gene expression, DNA damage repair and cell...
Main Authors: | Christopher J Millard, Niranjan Varma, Almutasem Saleh, Kyle Morris, Peter J Watson, Andrew R Bottrill, Louise Fairall, Corinne J Smith, John WR Schwabe |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-04-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/13941 |
Similar Items
-
RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes
by: Nathan R Rose, et al.
Published: (2016-10-01) -
The NuRD Complex in Neurodevelopment and Disease: A Case of Sliding Doors
by: Paraskevi Boulasiki, et al.
Published: (2023-04-01) -
The LINC Complex Inhibits Excessive Chromatin Repression
by: Daria Amiad Pavlov, et al.
Published: (2023-03-01) -
Disintegration of the NuRD Complex in Primary Human Muscle Stem Cells in Critical Illness Myopathy
by: Joanna Schneider, et al.
Published: (2023-02-01) -
Chromatin condensation retains the osteogenic transcription factor, RUNX2, in the nucleus of human mesenchymal stem cells
by: Masashi YAMAZAKI, et al.
Published: (2020-05-01)