SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and DifferentiationSummary

SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and DifferentiationSummary

Background and Aims: Intestinal mucosa undergoes a continual process of proliferation, differentiation, and apoptosis. Disruption of this homeostasis is associated with disorders such as inflammatory bowel disease (IBD). We investigated the role of Sirtuin 2 (SIRT2), a NAD-dependent protein deacetyl...

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Bibliographic Details
Main Authors: Chang Li, Yuning Zhou, Piotr Rychahou, Heidi L. Weiss, Eun Y. Lee, Courtney L. Perry, Terrence A. Barrett, Qingding Wang, B. Mark Evers
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Sirtuin
IEC
Intestinal Epithelial Cells
Wnt/β-Catenin
Intestinal Homeostasis
Mouse Model
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20300047

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