Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university

Abstract Introduction Pleural diseases involve the parietal and visceral pleura and may be of either inflammatory or malignant origin, with pleural effusions. Medical thoracoscopy (MT) is a procedure involving internal examination and biopsy of masses within the pleural and thoracic cavity. It is a...

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Main Authors: Abeer S. E. Mohamed, Neveen M. Amin, Mahmoud El-Batanouny
Format: Article
Language:English
Published: SpringerOpen 2017-07-01
Series:The Egyptian Journal of Bronchology
Subjects:
Online Access:http://link.springer.com/article/10.4103/ejb.ejb_87_16
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author Abeer S. E. Mohamed
Neveen M. Amin
Mahmoud El-Batanouny
author_facet Abeer S. E. Mohamed
Neveen M. Amin
Mahmoud El-Batanouny
author_sort Abeer S. E. Mohamed
collection DOAJ
description Abstract Introduction Pleural diseases involve the parietal and visceral pleura and may be of either inflammatory or malignant origin, with pleural effusions. Medical thoracoscopy (MT) is a procedure involving internal examination and biopsy of masses within the pleural and thoracic cavity. It is a valuable tool that enables a wide variety of diagnostic and therapeutic procedures. Aim The aim of this work was to assess the role of MT in patients with exudative undiagnosed pleural effusion. Patients and methods A total of 42 patients with undiagnosed exudative pleural effusion were admitted to Chest Department, Faculty of Medicine, Beni-Suef University. They were subjected to written informed consent,full history, clinical examination, sputum analysis, chest radiography, chest computed tomography, ECG, routine liver and kidney functions tests, complete blood count, coagulation profile, viral markers, and Tuberculin test. Diagnostic thoracentesis was done. The pleural fluid was subjected to testing for sugar, protein, lactate dehydrogenase, adenosine deaminase, cytopathology, Gram’s stain, and acid-fast bacilli smear and culture. Patients in whom the pleural effusion remained undiagnosed were subjected to MT. Results This study was applied on 42 patients with inconclusive cytological results: 20 were malignant (nine malignant pleural mesothelioma and 11 metastases), five had tuberculous pleurisy, eight had empyema, and nine had nonspecific pleurisy. Regarding pleural fluid cytological analysis, five cases were positive for atypical mesothelial cells. Conclusion MT is a valuable tool in the diagnosis of undiagnosed exudative pleural effusion. It is simple and safe, with high diagnostic yield and lower complication rates.
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spelling doaj.art-4ecb49de02e14422b41e8b665339ce4b2022-12-21T17:50:25ZengSpringerOpenThe Egyptian Journal of Bronchology1687-84262314-85512017-07-0111327628210.4103/ejb.ejb_87_16Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef universityAbeer S. E. Mohamed0Neveen M. Amin1Mahmoud El-Batanouny2Department of Chest, Faculty of Medicine, Beni-Suef UniversityDepartment of Chest, Faculty of Medicine, Beni-Suef UniversityDepartment of Chest, Faculty of Medicine, Beni-Suef UniversityAbstract Introduction Pleural diseases involve the parietal and visceral pleura and may be of either inflammatory or malignant origin, with pleural effusions. Medical thoracoscopy (MT) is a procedure involving internal examination and biopsy of masses within the pleural and thoracic cavity. It is a valuable tool that enables a wide variety of diagnostic and therapeutic procedures. Aim The aim of this work was to assess the role of MT in patients with exudative undiagnosed pleural effusion. Patients and methods A total of 42 patients with undiagnosed exudative pleural effusion were admitted to Chest Department, Faculty of Medicine, Beni-Suef University. They were subjected to written informed consent,full history, clinical examination, sputum analysis, chest radiography, chest computed tomography, ECG, routine liver and kidney functions tests, complete blood count, coagulation profile, viral markers, and Tuberculin test. Diagnostic thoracentesis was done. The pleural fluid was subjected to testing for sugar, protein, lactate dehydrogenase, adenosine deaminase, cytopathology, Gram’s stain, and acid-fast bacilli smear and culture. Patients in whom the pleural effusion remained undiagnosed were subjected to MT. Results This study was applied on 42 patients with inconclusive cytological results: 20 were malignant (nine malignant pleural mesothelioma and 11 metastases), five had tuberculous pleurisy, eight had empyema, and nine had nonspecific pleurisy. Regarding pleural fluid cytological analysis, five cases were positive for atypical mesothelial cells. Conclusion MT is a valuable tool in the diagnosis of undiagnosed exudative pleural effusion. It is simple and safe, with high diagnostic yield and lower complication rates.http://link.springer.com/article/10.4103/ejb.ejb_87_16mesotheliomapleural effusionthoracoscopy
spellingShingle Abeer S. E. Mohamed
Neveen M. Amin
Mahmoud El-Batanouny
Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university
The Egyptian Journal of Bronchology
mesothelioma
pleural effusion
thoracoscopy
title Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university
title_full Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university
title_fullStr Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university
title_full_unstemmed Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university
title_short Utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni-suef university
title_sort utility of medical thoracoscopy in patients with undiagnosed pleural effusion in chest department in beni suef university
topic mesothelioma
pleural effusion
thoracoscopy
url http://link.springer.com/article/10.4103/ejb.ejb_87_16
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