Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients
Objective To investigate the diagnosis and treatment of neurofibromatosis type2(NF2). Methods The clinical manifestations, magnetic resonance imaging(MRI) findings, and treatment of 4 patients with surgically and pathologically-confirmed NF2-associated bilateral acoustic neufibroma were retrospec...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2020-12-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200298.pdf |
| _version_ | 1797365662040981504 |
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| author | YANG Chang-li, TU Guo-long, XIA Ying |
| author_facet | YANG Chang-li, TU Guo-long, XIA Ying |
| author_sort | YANG Chang-li, TU Guo-long, XIA Ying |
| collection | DOAJ |
| description | Objective To investigate the diagnosis and treatment of neurofibromatosis type2(NF2). Methods The clinical manifestations, magnetic resonance imaging(MRI) findings, and treatment of 4 patients with surgically and pathologically-confirmed NF2-associated bilateral acoustic neufibroma were retrospectively analyzed,along with literature review. Results Bilateral acoustic neuroma was the mainly clinical manifestation in these four NF2 patients,although unilateral acoustic neuroma and schwannoma have also been described in literature.Microsurgery remains the mainstream treatment for NF2. Conclusions NF2 has unique clinical manifestations and MRI findings. It is mainly diagnosed by MRI and treated by surgery.However, the timing of surgery should be individualized and pay attention to the protection of the hearing at one side. |
| first_indexed | 2024-03-08T16:52:53Z |
| format | Article |
| id | doaj.art-4ecccebad8624ccc97aca59b9857fd9c |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T16:52:53Z |
| publishDate | 2020-12-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-4ecccebad8624ccc97aca59b9857fd9c2024-01-05T03:17:50ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252020-12-01401216771680Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patientsYANG Chang-li, TU Guo-long, XIA Ying01. Department of Neurosurgery,Second People's Hospital of Hainan Province, Wuzhishan 572299; ;2. Department of Neurosurgery, Haikou Hospital Affiliated to Xiangya Medical College, Central South University, Haikou 570208, ChinaObjective To investigate the diagnosis and treatment of neurofibromatosis type2(NF2). Methods The clinical manifestations, magnetic resonance imaging(MRI) findings, and treatment of 4 patients with surgically and pathologically-confirmed NF2-associated bilateral acoustic neufibroma were retrospectively analyzed,along with literature review. Results Bilateral acoustic neuroma was the mainly clinical manifestation in these four NF2 patients,although unilateral acoustic neuroma and schwannoma have also been described in literature.Microsurgery remains the mainstream treatment for NF2. Conclusions NF2 has unique clinical manifestations and MRI findings. It is mainly diagnosed by MRI and treated by surgery.However, the timing of surgery should be individualized and pay attention to the protection of the hearing at one side.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200298.pdfneurofibromatosis type 2|mri|treatment experience |
| spellingShingle | YANG Chang-li, TU Guo-long, XIA Ying Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients Jichu yixue yu linchuang neurofibromatosis type 2|mri|treatment experience |
| title | Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients |
| title_full | Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients |
| title_fullStr | Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients |
| title_full_unstemmed | Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients |
| title_short | Clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2: a retrospective analysis of 4 patients |
| title_sort | clinical diagnosis and treatment of bitaleral acoustic neurofibromatosis type 2 a retrospective analysis of 4 patients |
| topic | neurofibromatosis type 2|mri|treatment experience |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200298.pdf |
| work_keys_str_mv | AT yangchanglituguolongxiaying clinicaldiagnosisandtreatmentofbitaleralacousticneurofibromatosistype2aretrospectiveanalysisof4patients |