Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma
Glioblastoma (GBM) is the most malignant and aggressive form of glioma and is associated with a poor survival rate. Latest generation Tumour Necrosis Factor Related Apoptosis-Inducing Ligand (TRAIL)-based therapeutics potently induce apoptosis in cancer cells, including GBM cells, by binding to deat...
প্রধান লেখক: | , , , , , , |
---|---|
বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
MDPI AG
2021-12-01
|
মালা: | Molecules |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://www.mdpi.com/1420-3049/26/24/7582 |