Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma
Glioblastoma (GBM) is the most malignant and aggressive form of glioma and is associated with a poor survival rate. Latest generation Tumour Necrosis Factor Related Apoptosis-Inducing Ligand (TRAIL)-based therapeutics potently induce apoptosis in cancer cells, including GBM cells, by binding to deat...
Váldodahkkit: | , , , , , , |
---|---|
Materiálatiipa: | Artihkal |
Giella: | English |
Almmustuhtton: |
MDPI AG
2021-12-01
|
Ráidu: | Molecules |
Fáttát: | |
Liŋkkat: | https://www.mdpi.com/1420-3049/26/24/7582 |