The impact of frailty in aortic valve surgery

Abstract Background Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other...

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Main Authors: Elisabet Berastegui Garcia, Maria Luisa Camara Rosell, Enrique Moret Ruiz, Irma Casas Garcia, Sara Badia Gamarra, Claudio Fernandez Gallego, Luis Delgado Ramis, Ignasi Julia Almill, Anna Llorens Ferrer, Bernat Romero Ferrer, Antoni Bayes Genis, Christian Muñoz Guijosa
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Geriatrics
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Online Access:http://link.springer.com/article/10.1186/s12877-020-01716-3
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author Elisabet Berastegui Garcia
Maria Luisa Camara Rosell
Enrique Moret Ruiz
Irma Casas Garcia
Sara Badia Gamarra
Claudio Fernandez Gallego
Luis Delgado Ramis
Ignasi Julia Almill
Anna Llorens Ferrer
Bernat Romero Ferrer
Antoni Bayes Genis
Christian Muñoz Guijosa
author_facet Elisabet Berastegui Garcia
Maria Luisa Camara Rosell
Enrique Moret Ruiz
Irma Casas Garcia
Sara Badia Gamarra
Claudio Fernandez Gallego
Luis Delgado Ramis
Ignasi Julia Almill
Anna Llorens Ferrer
Bernat Romero Ferrer
Antoni Bayes Genis
Christian Muñoz Guijosa
author_sort Elisabet Berastegui Garcia
collection DOAJ
description Abstract Background Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other surgical-risk-scales and individual features of frailty in cardiac aortic valve surgery. Methods Prospective study. From May-2014 to February-2016, we collected 200 patients who underwent aortic valve replacement, either surgically or transcatheter. At 1-year follow-up, quality of life measurements were recorded using the EQ-5D (EuroQol). Univariate and multivariate analyses correlated preoperative condition, features of frailty and predicted risk scores with mortality, morbidity and quality of life at 1 year of follow-up. Results Mean age 78.2y, 56%male. Mean-preoperative-scores: FRAIL scale 1.5(SD 1.02), STS 2.9(SD 1.13), BI 93.8(SD 7.3), ESlog I 12.8(SD 8.5) and GS 7.3 s (SD 1.9). Morbidity at discharge, 6 m and 1 year was 51, 14 and 28%. Mortality 4%. Survival at 6 m/ 1-y was 97% / 88%. Complication-rate was higher in TAVI group due to-vascular complications. Renal dysfunction, anemia, social dependence and GS slower than 7 s were associated with morbidity. On multivariate analysis adjusted STS, BI and GS speed were statistically significant. Quality of life at 1-year follow-up adjusted for age and prosthesis type showed a significant association with STS and FRAIL scale scores. Conclusions Frailty increases surgical risk and is associated with higher morbidity. Preoperative GS slower 7 s, and STS and FRAIL scale scores seem to be reliable predictors of quality of life at 1-year follow-up.
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spelling doaj.art-4ed627cee03646469a5ee805bfccb5882022-12-22T00:11:26ZengBMCBMC Geriatrics1471-23182020-10-0120111010.1186/s12877-020-01716-3The impact of frailty in aortic valve surgeryElisabet Berastegui Garcia0Maria Luisa Camara Rosell1Enrique Moret Ruiz2Irma Casas Garcia3Sara Badia Gamarra4Claudio Fernandez Gallego5Luis Delgado Ramis6Ignasi Julia Almill7Anna Llorens Ferrer8Bernat Romero Ferrer9Antoni Bayes Genis10Christian Muñoz Guijosa11Cardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolAnesthesiology Department, Hospital Universitari Germans Trias i PujolPreventive Medicine Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolCardiovascular Institut, Hospital Universitari Germans Trias I PujolCardiac Surgery Department, Hospital Universitari Germans Trias i PujolAbstract Background Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other surgical-risk-scales and individual features of frailty in cardiac aortic valve surgery. Methods Prospective study. From May-2014 to February-2016, we collected 200 patients who underwent aortic valve replacement, either surgically or transcatheter. At 1-year follow-up, quality of life measurements were recorded using the EQ-5D (EuroQol). Univariate and multivariate analyses correlated preoperative condition, features of frailty and predicted risk scores with mortality, morbidity and quality of life at 1 year of follow-up. Results Mean age 78.2y, 56%male. Mean-preoperative-scores: FRAIL scale 1.5(SD 1.02), STS 2.9(SD 1.13), BI 93.8(SD 7.3), ESlog I 12.8(SD 8.5) and GS 7.3 s (SD 1.9). Morbidity at discharge, 6 m and 1 year was 51, 14 and 28%. Mortality 4%. Survival at 6 m/ 1-y was 97% / 88%. Complication-rate was higher in TAVI group due to-vascular complications. Renal dysfunction, anemia, social dependence and GS slower than 7 s were associated with morbidity. On multivariate analysis adjusted STS, BI and GS speed were statistically significant. Quality of life at 1-year follow-up adjusted for age and prosthesis type showed a significant association with STS and FRAIL scale scores. Conclusions Frailty increases surgical risk and is associated with higher morbidity. Preoperative GS slower 7 s, and STS and FRAIL scale scores seem to be reliable predictors of quality of life at 1-year follow-up.http://link.springer.com/article/10.1186/s12877-020-01716-3Aortic valve replacementFrailtyRisk scales
spellingShingle Elisabet Berastegui Garcia
Maria Luisa Camara Rosell
Enrique Moret Ruiz
Irma Casas Garcia
Sara Badia Gamarra
Claudio Fernandez Gallego
Luis Delgado Ramis
Ignasi Julia Almill
Anna Llorens Ferrer
Bernat Romero Ferrer
Antoni Bayes Genis
Christian Muñoz Guijosa
The impact of frailty in aortic valve surgery
BMC Geriatrics
Aortic valve replacement
Frailty
Risk scales
title The impact of frailty in aortic valve surgery
title_full The impact of frailty in aortic valve surgery
title_fullStr The impact of frailty in aortic valve surgery
title_full_unstemmed The impact of frailty in aortic valve surgery
title_short The impact of frailty in aortic valve surgery
title_sort impact of frailty in aortic valve surgery
topic Aortic valve replacement
Frailty
Risk scales
url http://link.springer.com/article/10.1186/s12877-020-01716-3
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