Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020
Abstract Background Esophageal cancer (EC) is a global health problem. Asia represents a huge burden of EC globally, and incidence and mortality vary considerably across different Asian regions. Methods Data on incidence, mortality, and preference were extracted from GLOBOCAN 2020. Age‐standardized...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-04-01
|
| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.14835 |
| _version_ | 1797265175712104448 |
|---|---|
| author | Hongcheng Zhu Zezhou Wang Bingbin Deng Miao Mo Honggang Wang Ke Chen Haoxuan Wu Ting Ye Boyan Wang Dashan Ai Shennan Hao Ihsuan Tseng Kuaile Zhao |
| author_facet | Hongcheng Zhu Zezhou Wang Bingbin Deng Miao Mo Honggang Wang Ke Chen Haoxuan Wu Ting Ye Boyan Wang Dashan Ai Shennan Hao Ihsuan Tseng Kuaile Zhao |
| author_sort | Hongcheng Zhu |
| collection | DOAJ |
| description | Abstract Background Esophageal cancer (EC) is a global health problem. Asia represents a huge burden of EC globally, and incidence and mortality vary considerably across different Asian regions. Methods Data on incidence, mortality, and preference were extracted from GLOBOCAN 2020. Age‐standardized incidence and mortality rates were calculated overall by sex, age, country, region, and continent. The predicted burden of incidence and mortality in 2040 was calculated based on global demographic projections. Results It was estimated there were 481 552 new cases of and 434 363 deaths from EC in Asia in 2020, accounting for 79.7% and 79.8% of world EC cases and deaths, respectively. EC incidence and mortality in Asia ranked the highest among all continents. Eastern Asia represents the highest age‐standardized world incidence rate (ASWIR) of 12.3 per 100 000 for all Asian regions. Western Asia represents the lowest ASWIR of 1.7 per 100 000, accounting for 0.7% of the globe. There exist obvious differences in epidemiological features in Asian countries, including incidence, mortality, prevalence, and mortality incidence ratio. There is forecast to be up to 781 000 new cases of EC in Asia by 2040, with increasing rates of 63% for incidence and 72% for mortality from 2020. Conclusions Asia has an increasing number of EC cases and deaths. Strategies for targeting in high‐incidence areas, the elderly, and survival should be prioritized to reduce the global EC burden, especially in low‐ and middle‐income countries in Asia. |
| first_indexed | 2024-04-25T00:40:37Z |
| format | Article |
| id | doaj.art-4ed6665f69604914b452e0a011ddc7f2 |
| institution | Directory Open Access Journal |
| issn | 1759-7706 1759-7714 |
| language | English |
| last_indexed | 2024-04-25T00:40:37Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj.art-4ed6665f69604914b452e0a011ddc7f22024-03-12T09:21:48ZengWileyThoracic Cancer1759-77061759-77142023-04-011411992100310.1111/1759-7714.14835Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020Hongcheng Zhu0Zezhou Wang1Bingbin Deng2Miao Mo3Honggang Wang4Ke Chen5Haoxuan Wu6Ting Ye7Boyan Wang8Dashan Ai9Shennan Hao10Ihsuan Tseng11Kuaile Zhao12Department of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai ChinaDepartment of Oncology, Shanghai Medical College Fudan University Shanghai ChinaDepartment of Radiotherapy and Oncology The Second Affiliated Hospital of Soochow University Suzhou ChinaDepartment of Oncology, Shanghai Medical College Fudan University Shanghai ChinaDepartment of Gastroenterology The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University Huai'an ChinaDepartment of Oncology, Shanghai Medical College Fudan University Shanghai ChinaDepartment of Oncology, Shanghai Medical College Fudan University Shanghai ChinaDepartment of Oncology, Shanghai Medical College Fudan University Shanghai ChinaDepartment of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai ChinaDepartment of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai ChinaDepartment of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai ChinaDepartment of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai ChinaDepartment of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai ChinaAbstract Background Esophageal cancer (EC) is a global health problem. Asia represents a huge burden of EC globally, and incidence and mortality vary considerably across different Asian regions. Methods Data on incidence, mortality, and preference were extracted from GLOBOCAN 2020. Age‐standardized incidence and mortality rates were calculated overall by sex, age, country, region, and continent. The predicted burden of incidence and mortality in 2040 was calculated based on global demographic projections. Results It was estimated there were 481 552 new cases of and 434 363 deaths from EC in Asia in 2020, accounting for 79.7% and 79.8% of world EC cases and deaths, respectively. EC incidence and mortality in Asia ranked the highest among all continents. Eastern Asia represents the highest age‐standardized world incidence rate (ASWIR) of 12.3 per 100 000 for all Asian regions. Western Asia represents the lowest ASWIR of 1.7 per 100 000, accounting for 0.7% of the globe. There exist obvious differences in epidemiological features in Asian countries, including incidence, mortality, prevalence, and mortality incidence ratio. There is forecast to be up to 781 000 new cases of EC in Asia by 2040, with increasing rates of 63% for incidence and 72% for mortality from 2020. Conclusions Asia has an increasing number of EC cases and deaths. Strategies for targeting in high‐incidence areas, the elderly, and survival should be prioritized to reduce the global EC burden, especially in low‐ and middle‐income countries in Asia.https://doi.org/10.1111/1759-7714.14835Asiaepidemiologyesophageal cancergastrointestinal cancer |
| spellingShingle | Hongcheng Zhu Zezhou Wang Bingbin Deng Miao Mo Honggang Wang Ke Chen Haoxuan Wu Ting Ye Boyan Wang Dashan Ai Shennan Hao Ihsuan Tseng Kuaile Zhao Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020 Thoracic Cancer Asia epidemiology esophageal cancer gastrointestinal cancer |
| title | Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020 |
| title_full | Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020 |
| title_fullStr | Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020 |
| title_full_unstemmed | Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020 |
| title_short | Epidemiological landscape of esophageal cancer in Asia: Results from GLOBOCAN 2020 |
| title_sort | epidemiological landscape of esophageal cancer in asia results from globocan 2020 |
| topic | Asia epidemiology esophageal cancer gastrointestinal cancer |
| url | https://doi.org/10.1111/1759-7714.14835 |
| work_keys_str_mv | AT hongchengzhu epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT zezhouwang epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT bingbindeng epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT miaomo epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT honggangwang epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT kechen epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT haoxuanwu epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT tingye epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT boyanwang epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT dashanai epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT shennanhao epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT ihsuantseng epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 AT kuailezhao epidemiologicallandscapeofesophagealcancerinasiaresultsfromglobocan2020 |