Enhancing the Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies

Enhancing the Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies

Broad-spectrum antiviral therapies hold promise as a first-line defense against emerging viruses by blunting illness severity and spread until vaccines and virus-specific antivirals are developed. The nucleobase favipiravir, often discussed as a broad-spectrum inhibitor, was not effective in recent...

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Bibliographic Details
Main Authors: Ruben Soto-Acosta, Tiffany C. Edwards, Christine D. Dreis, Venkatramana D. Krishna, Maxim C-J. Cheeran, Li Qiu, Jiashu Xie, Laurent F. Bonnac, Robert J. Geraghty
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
nucleobase
antiviral
favipiravir
broad-spectrum
emerging viruses
antimetabolite
Online Access:https://www.mdpi.com/1999-4915/13/12/2508

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