A case of neuroleptic malignant syndrome following cardiac surgery
Neuroleptic malignant syndrome (NMS) is rare but sometimes causes life-threatening conditions. We report the case of a 53-year-old male patient who developed NMS following cardiac surgery. He was diagnosed with schizophrenia and pre- scribed blonanserin, chlorpromazine, and biperiden. From postopera...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
GESDAV
2017-06-01
|
| Series: | Archives of Clinical and Experimental Surgery |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=200625 |
| _version_ | 1797920122761904128 |
|---|---|
| author | Atsushi Tamura Hiroko Nakata Takamichi Yoshizaki Sho Kusadokoro |
| author_facet | Atsushi Tamura Hiroko Nakata Takamichi Yoshizaki Sho Kusadokoro |
| author_sort | Atsushi Tamura |
| collection | DOAJ |
| description | Neuroleptic malignant syndrome (NMS) is rare but sometimes causes life-threatening conditions. We report the case of a 53-year-old male patient who developed NMS following cardiac surgery. He was diagnosed with schizophrenia and pre- scribed blonanserin, chlorpromazine, and biperiden. From postoperative day 3, hyperthermia, disturbed consciousness, and involuntary movement were observed. Subsequently, his serum creatine phosphokinase (CPK) levels increased. After NMS was suspected, chlorpromazine and biperiden were stopped. From postoperative day 7, intravenous administration of dant- rolene was initiated. Following this treatment, his serum CPK levels gradually decreased, and the other symptoms improved. The treatment of NMS remains controversial. There is no evidence that dantrolene is effective for treating NMS; however, it may be one of the important options for treating NMS. We present the case and discuss the diagnosis and management of NMS following cardiac surgery. [Arch Clin Exp Surg 2017; 6(2.000): 117-119] |
| first_indexed | 2024-04-10T13:56:30Z |
| format | Article |
| id | doaj.art-4edc685bc55e4884b826f757e255ffe0 |
| institution | Directory Open Access Journal |
| issn | 2146-8133 |
| language | English |
| last_indexed | 2024-04-10T13:56:30Z |
| publishDate | 2017-06-01 |
| publisher | GESDAV |
| record_format | Article |
| series | Archives of Clinical and Experimental Surgery |
| spelling | doaj.art-4edc685bc55e4884b826f757e255ffe02023-02-15T16:10:28ZengGESDAVArchives of Clinical and Experimental Surgery2146-81332017-06-016211711910.5455/aces.20151012124332200625A case of neuroleptic malignant syndrome following cardiac surgeryAtsushi Tamura0Hiroko Nakata1Takamichi Yoshizaki2Sho Kusadokoro3Department of Cardiovascular Surgery, Yokosuka General Hospital Uwamachi, Yokosuka, Japan Department of Cardiovascular Surgery, Yokosuka General Hospital Uwamachi, Yokosuka, Japan Department of Cardiovascular Surgery, Yokosuka General Hospital Uwamachi, Yokosuka, Japan Department of Cardiovascular Surgery, Yokosuka General Hospital Uwamachi, Yokosuka, JapanNeuroleptic malignant syndrome (NMS) is rare but sometimes causes life-threatening conditions. We report the case of a 53-year-old male patient who developed NMS following cardiac surgery. He was diagnosed with schizophrenia and pre- scribed blonanserin, chlorpromazine, and biperiden. From postoperative day 3, hyperthermia, disturbed consciousness, and involuntary movement were observed. Subsequently, his serum creatine phosphokinase (CPK) levels increased. After NMS was suspected, chlorpromazine and biperiden were stopped. From postoperative day 7, intravenous administration of dant- rolene was initiated. Following this treatment, his serum CPK levels gradually decreased, and the other symptoms improved. The treatment of NMS remains controversial. There is no evidence that dantrolene is effective for treating NMS; however, it may be one of the important options for treating NMS. We present the case and discuss the diagnosis and management of NMS following cardiac surgery. [Arch Clin Exp Surg 2017; 6(2.000): 117-119]http://www.ejmanager.com/fulltextpdf.php?mno=200625Neuroleptic malignant syndromecardiac surgerydantrolene |
| spellingShingle | Atsushi Tamura Hiroko Nakata Takamichi Yoshizaki Sho Kusadokoro A case of neuroleptic malignant syndrome following cardiac surgery Archives of Clinical and Experimental Surgery Neuroleptic malignant syndrome cardiac surgery dantrolene |
| title | A case of neuroleptic malignant syndrome following cardiac surgery |
| title_full | A case of neuroleptic malignant syndrome following cardiac surgery |
| title_fullStr | A case of neuroleptic malignant syndrome following cardiac surgery |
| title_full_unstemmed | A case of neuroleptic malignant syndrome following cardiac surgery |
| title_short | A case of neuroleptic malignant syndrome following cardiac surgery |
| title_sort | case of neuroleptic malignant syndrome following cardiac surgery |
| topic | Neuroleptic malignant syndrome cardiac surgery dantrolene |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=200625 |
| work_keys_str_mv | AT atsushitamura acaseofneurolepticmalignantsyndromefollowingcardiacsurgery AT hirokonakata acaseofneurolepticmalignantsyndromefollowingcardiacsurgery AT takamichiyoshizaki acaseofneurolepticmalignantsyndromefollowingcardiacsurgery AT shokusadokoro acaseofneurolepticmalignantsyndromefollowingcardiacsurgery AT atsushitamura caseofneurolepticmalignantsyndromefollowingcardiacsurgery AT hirokonakata caseofneurolepticmalignantsyndromefollowingcardiacsurgery AT takamichiyoshizaki caseofneurolepticmalignantsyndromefollowingcardiacsurgery AT shokusadokoro caseofneurolepticmalignantsyndromefollowingcardiacsurgery |