Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas aeruginosaResearch in context

Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas aeruginosaResearch in context

Summary: Background: Pseudomonas aeruginosa is an opportunistic pathogen consisting of three phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific evolutionary dynamics across available and also new P. aeruginosa genomes. Methods: In this genomic analysis, we first genera...

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Bibliographic Details
Main Authors: João Botelho, Leif Tüffers, Janina Fuss, Florian Buchholz, Christian Utpatel, Jens Klockgether, Stefan Niemann, Burkhard Tümmler, Hinrich Schulenburg
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:EBioMedicine
Subjects:
Pangenome
Pseudomonas aeruginosa
Regions of genome plasticity
Antibiotic resistance
CRISPR-Cas systems
Defence systems
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642300097X

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http://www.sciencedirect.com/science/article/pii/S235239642300097X

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