Encephalitis, Ontario, Canada, 2002–2013

Encephalitis, a brain inflammation leading to severe illness and often death, is caused by >100 pathogens. To assess the incidence and trends of encephalitis in Ontario, Canada, we obtained data on 6,463 Ontario encephalitis hospitalizations from the hospital Discharge Abstract Database for April...

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Main Authors: Alyssa S. Parpia, Ye Li, Cynthia Chen, Badal Dhar, Natasha S. Crowcroft
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2016-03-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/22/3/15-1545_article
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author Alyssa S. Parpia
Ye Li
Cynthia Chen
Badal Dhar
Natasha S. Crowcroft
author_facet Alyssa S. Parpia
Ye Li
Cynthia Chen
Badal Dhar
Natasha S. Crowcroft
author_sort Alyssa S. Parpia
collection DOAJ
description Encephalitis, a brain inflammation leading to severe illness and often death, is caused by >100 pathogens. To assess the incidence and trends of encephalitis in Ontario, Canada, we obtained data on 6,463 Ontario encephalitis hospitalizations from the hospital Discharge Abstract Database for April 2002–December 2013 and analyzed these data using multiple negative binomial regression. The estimated crude incidence of all-cause encephalitis in Ontario was ≈4.3 cases/100,000 persons/year. Incidence rates for infants <1 year of age and adults >65 years were 3.9 and 3.0 times that of adults 20–44 years of age, respectively. Incidence peaks during August–September in 2002 and 2012 resulted primarily from encephalitis of unknown cause and viral encephalitis. Encephalitis occurred more frequently in older age groups and less frequently in women in Ontario when compared to England, but despite differences in population, vector-borne diseases, climate, and geography, the epidemiology was overall remarkably similar in the two regions.
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spelling doaj.art-4ee92d5415494254903440e705618bff2022-12-22T01:13:54ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592016-03-0122342643210.3201/eid2203.151545Encephalitis, Ontario, Canada, 2002–2013Alyssa S. ParpiaYe LiCynthia ChenBadal DharNatasha S. CrowcroftEncephalitis, a brain inflammation leading to severe illness and often death, is caused by >100 pathogens. To assess the incidence and trends of encephalitis in Ontario, Canada, we obtained data on 6,463 Ontario encephalitis hospitalizations from the hospital Discharge Abstract Database for April 2002–December 2013 and analyzed these data using multiple negative binomial regression. The estimated crude incidence of all-cause encephalitis in Ontario was ≈4.3 cases/100,000 persons/year. Incidence rates for infants <1 year of age and adults >65 years were 3.9 and 3.0 times that of adults 20–44 years of age, respectively. Incidence peaks during August–September in 2002 and 2012 resulted primarily from encephalitis of unknown cause and viral encephalitis. Encephalitis occurred more frequently in older age groups and less frequently in women in Ontario when compared to England, but despite differences in population, vector-borne diseases, climate, and geography, the epidemiology was overall remarkably similar in the two regions.https://wwwnc.cdc.gov/eid/article/22/3/15-1545_articleencephalitisincidenceepidemiologyetiologyOntario CanadaEngland
spellingShingle Alyssa S. Parpia
Ye Li
Cynthia Chen
Badal Dhar
Natasha S. Crowcroft
Encephalitis, Ontario, Canada, 2002–2013
Emerging Infectious Diseases
encephalitis
incidence
epidemiology
etiology
Ontario Canada
England
title Encephalitis, Ontario, Canada, 2002–2013
title_full Encephalitis, Ontario, Canada, 2002–2013
title_fullStr Encephalitis, Ontario, Canada, 2002–2013
title_full_unstemmed Encephalitis, Ontario, Canada, 2002–2013
title_short Encephalitis, Ontario, Canada, 2002–2013
title_sort encephalitis ontario canada 2002 2013
topic encephalitis
incidence
epidemiology
etiology
Ontario Canada
England
url https://wwwnc.cdc.gov/eid/article/22/3/15-1545_article
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