Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells.

Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells.

Although many chemotherapeutic strategies against cancer have been developed, pancreatic cancer is one of the most aggressive and intractable types of malignancies. Therefore, new strategies and anti-cancer agents are necessary to treat this disease. Metformin is a widely used drug for type-2 diabet...

Detaylı Bibliyografya
Asıl Yazarlar:	Ryoichi Tanaka, Mitsuhiro Tomosugi, Mano Horinaka, Yoshihiro Sowa, Toshiyuki Sakai
Materyal Türü:	Makale
Dil:	English
Baskı/Yayın Bilgisi:	Public Library of Science (PLoS) 2015-01-01
Seri Bilgileri:	PLoS ONE
Online Erişim:	http://europepmc.org/articles/PMC4425682?pdf=render

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