Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus
Plants from the <i>Chrysanthemum</i> genus are rich sources of chemical diversity and, in recent years, have been the focus of research on natural products chemistry. Sesquiterpenoids are one of the major classes of chemical constituents reported from this genus. To date, more than 135 s...
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MDPI AG
2021-05-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/10/3038 |
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| author | Sai Jiang Mengyun Wang Zichen Jiang Salman Zafar Qian Xie Yupei Yang Yang Liu Hanwen Yuan Yuqing Jian Wei Wang |
| author_facet | Sai Jiang Mengyun Wang Zichen Jiang Salman Zafar Qian Xie Yupei Yang Yang Liu Hanwen Yuan Yuqing Jian Wei Wang |
| author_sort | Sai Jiang |
| collection | DOAJ |
| description | Plants from the <i>Chrysanthemum</i> genus are rich sources of chemical diversity and, in recent years, have been the focus of research on natural products chemistry. Sesquiterpenoids are one of the major classes of chemical constituents reported from this genus. To date, more than 135 sesquiterpenoids have been isolated and identified from the whole genus. These include 26 germacrane-type, 26 eudesmane-type, 64 guaianolide-type, 4 bisabolane-type, and 15 other-type sesquiterpenoids. Pharmacological studies have proven the biological potential of sesquiterpenoids isolated from <i>Chrysanthemum</i> species, reporting anti-inflammatory, antibacterial, antitumor, insecticidal, and antiviral activities for these interesting molecules. In this paper, we provide information on the chemistry and bioactivity of sesquiterpenoids obtained from the <i>Chrysanthemum</i> genus which could be used as the scientific basis for their future development and utilization. |
| first_indexed | 2024-03-10T11:15:05Z |
| format | Article |
| id | doaj.art-4eee3b6ae2af461591a30d29714e6df3 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T11:15:05Z |
| publishDate | 2021-05-01 |
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| series | Molecules |
| spelling | doaj.art-4eee3b6ae2af461591a30d29714e6df32023-11-21T20:28:58ZengMDPI AGMolecules1420-30492021-05-012610303810.3390/molecules26103038Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> GenusSai Jiang0Mengyun Wang1Zichen Jiang2Salman Zafar3Qian Xie4Yupei Yang5Yang Liu6Hanwen Yuan7Yuqing Jian8Wei Wang9TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaDivision of Biological Sciences, University of California San Diego, San Diego, CA 95101, USAInstitute of Chemical Sciences, University of Peshawar, Peshawar 25120, PakistanTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaTCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Materia Medica Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, ChinaPlants from the <i>Chrysanthemum</i> genus are rich sources of chemical diversity and, in recent years, have been the focus of research on natural products chemistry. Sesquiterpenoids are one of the major classes of chemical constituents reported from this genus. To date, more than 135 sesquiterpenoids have been isolated and identified from the whole genus. These include 26 germacrane-type, 26 eudesmane-type, 64 guaianolide-type, 4 bisabolane-type, and 15 other-type sesquiterpenoids. Pharmacological studies have proven the biological potential of sesquiterpenoids isolated from <i>Chrysanthemum</i> species, reporting anti-inflammatory, antibacterial, antitumor, insecticidal, and antiviral activities for these interesting molecules. In this paper, we provide information on the chemistry and bioactivity of sesquiterpenoids obtained from the <i>Chrysanthemum</i> genus which could be used as the scientific basis for their future development and utilization.https://www.mdpi.com/1420-3049/26/10/3038<i>Chrysanthemum</i> genussesquiterpenoidsbiosynthetic pathwaypharmacological effects |
| spellingShingle | Sai Jiang Mengyun Wang Zichen Jiang Salman Zafar Qian Xie Yupei Yang Yang Liu Hanwen Yuan Yuqing Jian Wei Wang Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus Molecules <i>Chrysanthemum</i> genus sesquiterpenoids biosynthetic pathway pharmacological effects |
| title | Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus |
| title_full | Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus |
| title_fullStr | Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus |
| title_full_unstemmed | Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus |
| title_short | Chemistry and Pharmacological Activity of Sesquiterpenoids from the <i>Chrysanthemum</i> Genus |
| title_sort | chemistry and pharmacological activity of sesquiterpenoids from the i chrysanthemum i genus |
| topic | <i>Chrysanthemum</i> genus sesquiterpenoids biosynthetic pathway pharmacological effects |
| url | https://www.mdpi.com/1420-3049/26/10/3038 |
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