Baricitinib protects mice from sepsis-induced cardiac dysfunction and multiple-organ failure

Baricitinib protects mice from sepsis-induced cardiac dysfunction and multiple-organ failure

Sepsis is one of the major complications of surgery resulting in high morbidity and mortality, but there are no specific therapies for sepsis-induced organ dysfunction. Data obtained under Gene Expression Omnibus accession GSE131761 were re-analyzed and showed an increased gene expression of Janus K...

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Bibliographic Details
Main Authors: Chiara Verra, Shireen Mohammad, Gustavo Ferreira Alves, Elisa Porchietto, Sina Maren Coldewey, Massimo Collino, Christoph Thiemermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
sepsis
baricitinib
Janus Kinase
cardiac dysfunction
multiple-organ failure
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1223014/full

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