Bidirectional cingulate-dependent danger information transfer across rats.
Social transmission of freezing behavior has been conceived of as a one-way phenomenon in which an observer "catches" the fear of another. Here, we use a paradigm in which an observer rat witnesses another rat receiving electroshocks. Bayesian model comparison and Granger causality show th...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2019-12-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.3000524 |
| _version_ | 1818361494437363712 |
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| author | Yingying Han Rune Bruls Efe Soyman Rajat Mani Thomas Vasiliki Pentaraki Naomi Jelinek Mirjam Heinemans Iege Bassez Sam Verschooren Illanah Pruis Thijs Van Lierde Nathaly Carrillo Valeria Gazzola Maria Carrillo Christian Keysers |
| author_facet | Yingying Han Rune Bruls Efe Soyman Rajat Mani Thomas Vasiliki Pentaraki Naomi Jelinek Mirjam Heinemans Iege Bassez Sam Verschooren Illanah Pruis Thijs Van Lierde Nathaly Carrillo Valeria Gazzola Maria Carrillo Christian Keysers |
| author_sort | Yingying Han |
| collection | DOAJ |
| description | Social transmission of freezing behavior has been conceived of as a one-way phenomenon in which an observer "catches" the fear of another. Here, we use a paradigm in which an observer rat witnesses another rat receiving electroshocks. Bayesian model comparison and Granger causality show that rats exchange information about danger in both directions: how the observer reacts to the demonstrator's distress also influences how the demonstrator responds to the danger. This was true to a similar extent across highly familiar and entirely unfamiliar rats but is stronger in animals preexposed to shocks. Injecting muscimol in the anterior cingulate of observers reduced freezing in the observers and in the demonstrators receiving the shocks. Using simulations, we support the notion that the coupling of freezing across rats could be selected for to more efficiently detect dangers in a group, in a way similar to cross-species eavesdropping. |
| first_indexed | 2024-12-13T21:17:35Z |
| format | Article |
| id | doaj.art-4ef0b97c043b4467adc1f8b6bfe7fef5 |
| institution | Directory Open Access Journal |
| issn | 1544-9173 1545-7885 |
| language | English |
| last_indexed | 2024-12-13T21:17:35Z |
| publishDate | 2019-12-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Biology |
| spelling | doaj.art-4ef0b97c043b4467adc1f8b6bfe7fef52022-12-21T23:31:12ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852019-12-011712e300052410.1371/journal.pbio.3000524Bidirectional cingulate-dependent danger information transfer across rats.Yingying HanRune BrulsEfe SoymanRajat Mani ThomasVasiliki PentarakiNaomi JelinekMirjam HeinemansIege BassezSam VerschoorenIllanah PruisThijs Van LierdeNathaly CarrilloValeria GazzolaMaria CarrilloChristian KeysersSocial transmission of freezing behavior has been conceived of as a one-way phenomenon in which an observer "catches" the fear of another. Here, we use a paradigm in which an observer rat witnesses another rat receiving electroshocks. Bayesian model comparison and Granger causality show that rats exchange information about danger in both directions: how the observer reacts to the demonstrator's distress also influences how the demonstrator responds to the danger. This was true to a similar extent across highly familiar and entirely unfamiliar rats but is stronger in animals preexposed to shocks. Injecting muscimol in the anterior cingulate of observers reduced freezing in the observers and in the demonstrators receiving the shocks. Using simulations, we support the notion that the coupling of freezing across rats could be selected for to more efficiently detect dangers in a group, in a way similar to cross-species eavesdropping.https://doi.org/10.1371/journal.pbio.3000524 |
| spellingShingle | Yingying Han Rune Bruls Efe Soyman Rajat Mani Thomas Vasiliki Pentaraki Naomi Jelinek Mirjam Heinemans Iege Bassez Sam Verschooren Illanah Pruis Thijs Van Lierde Nathaly Carrillo Valeria Gazzola Maria Carrillo Christian Keysers Bidirectional cingulate-dependent danger information transfer across rats. PLoS Biology |
| title | Bidirectional cingulate-dependent danger information transfer across rats. |
| title_full | Bidirectional cingulate-dependent danger information transfer across rats. |
| title_fullStr | Bidirectional cingulate-dependent danger information transfer across rats. |
| title_full_unstemmed | Bidirectional cingulate-dependent danger information transfer across rats. |
| title_short | Bidirectional cingulate-dependent danger information transfer across rats. |
| title_sort | bidirectional cingulate dependent danger information transfer across rats |
| url | https://doi.org/10.1371/journal.pbio.3000524 |
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