Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin

Improving vasculoprotective effects of MSCs in coronary microvessels – benefits of 3D culture, sub-populations and heparin

IntroductionOpening occluded coronary arteries in patients with myocardial infarction (MI) damages the delicate coronary microvessels through a process called myocardial ischaemia-reperfusion injury. Although mesenchymal stromal cells (MSCs) have the potential to limit this injury, clinical success...

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Bibliographic Details
Main Authors:	Kobkaew Bumroongthai, Dean P. J. Kavanagh, Paul Genever, Neena Kalia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Series:	Frontiers in Immunology
Subjects:	myocardial infarction myocardial ischaemia-reperfusion injury coronary microcirculation mesenchymal stem/stromal cells intravital microscopy neutrophils
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1257497/full

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