Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study

Abstract Background Healthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane review...

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Main Authors: Jesús López-Alcalde, Elena Stallings, Sheila Cabir Nunes, Abelardo Fernández Chávez, Mathilde Daheron, Xavier Bonfill Cosp, Javier Zamora
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Health Services Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12913-019-4001-9
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author Jesús López-Alcalde
Elena Stallings
Sheila Cabir Nunes
Abelardo Fernández Chávez
Mathilde Daheron
Xavier Bonfill Cosp
Javier Zamora
author_facet Jesús López-Alcalde
Elena Stallings
Sheila Cabir Nunes
Abelardo Fernández Chávez
Mathilde Daheron
Xavier Bonfill Cosp
Javier Zamora
author_sort Jesús López-Alcalde
collection DOAJ
description Abstract Background Healthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane reviews will limit their applicability and capacity to support informed decisions. This study aims to describe the extent to which Cochrane reviews of interventions for preventing HAIs consider sex and gender. Methods Methodology study appraising Cochrane reviews of interventions to prevent HAIs. Search methods: Cochrane Database of Systematic Reviews from 1995 (launch of the journal) to 31 December 2016. Two authors independently extracted data with EPPI-Reviewer 4 software, and independently appraised the sex/gender content of the reviews with the Sex and Gender Appraisal Tool for Systematic Reviews (SGAT-SR). Results This study included 113 reviews assessing the effects of interventions for preventing HAIs. 100 reviews (88%) used at least one sex or gender-related term. The terminology used was heterogeneous, being “sex” the term used in more reviews (51%). No review defined neither sex nor gender. Thus we could not assess the definitions provided. Consideration of sex and gender was practically absent in the included reviews; in fact, no review met all the applicable items of the SGAT-SR, and 51 reviews (50%) fulfilled no item. No review provided a complete description of the sex and the gender of the samples of the included studies. Only ten reviews (10%) planned to perform sex- and gender-based analysis and only three (3%) could complete the analysis. The method chosen was always the subgroup analysis based on sex (one review) or gender (two reviews). Three reviews (3%) considered sex or gender-related findings in the conclusions. Conclusion Consideration of sex and gender in Cochrane reviews of interventions for preventing HAIs was practically absent. This lack of attention to sex and gender reduces the quality of Cochrane reviews, and their applicability for all people: women and men, boys and girls, and people of diverse gender identities. Cochrane should attempt to address the shortfalls detected.
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spelling doaj.art-4ef5f3ad30ff4eb19e730df9ef82e9a02022-12-22T00:59:53ZengBMCBMC Health Services Research1472-69632019-03-0119111710.1186/s12913-019-4001-9Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology studyJesús López-Alcalde0Elena Stallings1Sheila Cabir Nunes2Abelardo Fernández Chávez3Mathilde Daheron4Xavier Bonfill Cosp5Javier Zamora6Department of Paediatrics, Obstetrics & Gynaecology and Preventative Medicine, Universitat Autònoma de BarcelonaClinical Biostatistics Unit, Hospital Universitario Ramón y Cajal (IRYCIS)Independent ResearcherPreventive medicine Unit, Hospital Universitario Ramón y CajalIndependent ResearcherIberoamerican Cochrane Centre, IIB Sant Pau, Universitat Autònoma de BarcelonaClinical Biostatistics Unit, Hospital Universitario Ramón y Cajal (IRYCIS)Abstract Background Healthcare-associated infections (HAIs) are common and increase morbidity, mortality, and healthcare costs. Their control continues to be an unresolved issue worldwide. HAIs epidemiology shows sex/gender differences. Thus the lack of consideration of sex/gender in Cochrane reviews will limit their applicability and capacity to support informed decisions. This study aims to describe the extent to which Cochrane reviews of interventions for preventing HAIs consider sex and gender. Methods Methodology study appraising Cochrane reviews of interventions to prevent HAIs. Search methods: Cochrane Database of Systematic Reviews from 1995 (launch of the journal) to 31 December 2016. Two authors independently extracted data with EPPI-Reviewer 4 software, and independently appraised the sex/gender content of the reviews with the Sex and Gender Appraisal Tool for Systematic Reviews (SGAT-SR). Results This study included 113 reviews assessing the effects of interventions for preventing HAIs. 100 reviews (88%) used at least one sex or gender-related term. The terminology used was heterogeneous, being “sex” the term used in more reviews (51%). No review defined neither sex nor gender. Thus we could not assess the definitions provided. Consideration of sex and gender was practically absent in the included reviews; in fact, no review met all the applicable items of the SGAT-SR, and 51 reviews (50%) fulfilled no item. No review provided a complete description of the sex and the gender of the samples of the included studies. Only ten reviews (10%) planned to perform sex- and gender-based analysis and only three (3%) could complete the analysis. The method chosen was always the subgroup analysis based on sex (one review) or gender (two reviews). Three reviews (3%) considered sex or gender-related findings in the conclusions. Conclusion Consideration of sex and gender in Cochrane reviews of interventions for preventing HAIs was practically absent. This lack of attention to sex and gender reduces the quality of Cochrane reviews, and their applicability for all people: women and men, boys and girls, and people of diverse gender identities. Cochrane should attempt to address the shortfalls detected.http://link.springer.com/article/10.1186/s12913-019-4001-9Systematic reviewsData extractionSexGenderSex/genderEquity
spellingShingle Jesús López-Alcalde
Elena Stallings
Sheila Cabir Nunes
Abelardo Fernández Chávez
Mathilde Daheron
Xavier Bonfill Cosp
Javier Zamora
Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
BMC Health Services Research
Systematic reviews
Data extraction
Sex
Gender
Sex/gender
Equity
title Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_full Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_fullStr Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_full_unstemmed Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_short Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study
title_sort consideration of sex and gender in cochrane reviews of interventions for preventing healthcare associated infections a methodology study
topic Systematic reviews
Data extraction
Sex
Gender
Sex/gender
Equity
url http://link.springer.com/article/10.1186/s12913-019-4001-9
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