Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19
Aim. To study clinical, medical history and paraclinical characteristics of patients with non-ST elevation myocardial infarction (NSTEMI) after coronavirus disease 2019 (COVID-19).Material and methods. The study included 209 patients with NSTEMI who were admitted to the Demikhov City Clinical Hospit...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2021-11-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3062 |
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| author | M. G. Chashchin A. Yu. Gorshkov O. M. Drapkina I. V. Kositsyna A. V. Golubev N. I. Chaus S. N. Perekhodov |
| author_facet | M. G. Chashchin A. Yu. Gorshkov O. M. Drapkina I. V. Kositsyna A. V. Golubev N. I. Chaus S. N. Perekhodov |
| author_sort | M. G. Chashchin |
| collection | DOAJ |
| description | Aim. To study clinical, medical history and paraclinical characteristics of patients with non-ST elevation myocardial infarction (NSTEMI) after coronavirus disease 2019 (COVID-19).Material and methods. The study included 209 patients with NSTEMI who were admitted to the Demikhov City Clinical Hospital (Moscow). The patients were divided into 2 groups: the experimental one (n=104) — those after COVID-19, the control one (n=105) — those without history of COVID-19. All patients underwent routine diagnostic investigations in accordance with current standards and clinical guidelines.Results. The mean age of patients in the experimental group was 61,8±12,2 years, while in the control one — 69,0±13,0 years (p<0,0001). Myocardial infarction developed 49 days [34.0; 82.0] after COVID-19. Prior exertional angina was observed in 76,9% of patients in the experimental group and in 88,6% in the control one (χ2 =4,97; p=0,0258). The level of C-reactive protein in the experimental group was 19,2 mg/l [4,9; 53,0], and in the control one — 5,6 mg/l [0,4; 21,8] (p=0,0007). The average troponin I level in the experimental group was 2,7 ng/ml [1,3; 8,0], while in the control one — 1,8 ng/ml [0,8; 3,5] (p=0,0091).Conclusion. Patients with NSTEMI after COVID-19 were significantly younger compared to patients without a history of COVID-19. They had less common exertional angina prior to MI, while C-reactive protein and troponin I levels were significantly higher than in the control group. In addition, in NSTEMI patients after COVID-19, the estimated pulmonary artery systolic pressure was significantly higher compared to patients without a history of COVID-19. |
| first_indexed | 2024-04-10T03:33:56Z |
| format | Article |
| id | doaj.art-4ef9c82ca7384803baca34bc01d6e517 |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2025-03-19T22:35:21Z |
| publishDate | 2021-11-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-4ef9c82ca7384803baca34bc01d6e5172024-10-17T12:21:41Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-11-0120710.15829/1728-8800-2021-30622388Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19M. G. Chashchin0A. Yu. Gorshkov1O. M. Drapkina2I. V. Kositsyna3A. V. Golubev4N. I. Chaus5S. N. Perekhodov6National Medical Research Center for Therapy and Preventive Medicine; Demikhov City Clinical HospitalNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineDemikhov City Clinical Hospital; A.I. Yevdokimov Moscow State University of Medicine and DentistryDemikhov City Clinical Hospital; A.I. Yevdokimov Moscow State University of Medicine and DentistryDemikhov City Clinical Hospital; Russian Medical Academy of Continuous Professional EducationDemikhov City Clinical Hospital; A.I. Yevdokimov Moscow State University of Medicine and DentistryAim. To study clinical, medical history and paraclinical characteristics of patients with non-ST elevation myocardial infarction (NSTEMI) after coronavirus disease 2019 (COVID-19).Material and methods. The study included 209 patients with NSTEMI who were admitted to the Demikhov City Clinical Hospital (Moscow). The patients were divided into 2 groups: the experimental one (n=104) — those after COVID-19, the control one (n=105) — those without history of COVID-19. All patients underwent routine diagnostic investigations in accordance with current standards and clinical guidelines.Results. The mean age of patients in the experimental group was 61,8±12,2 years, while in the control one — 69,0±13,0 years (p<0,0001). Myocardial infarction developed 49 days [34.0; 82.0] after COVID-19. Prior exertional angina was observed in 76,9% of patients in the experimental group and in 88,6% in the control one (χ2 =4,97; p=0,0258). The level of C-reactive protein in the experimental group was 19,2 mg/l [4,9; 53,0], and in the control one — 5,6 mg/l [0,4; 21,8] (p=0,0007). The average troponin I level in the experimental group was 2,7 ng/ml [1,3; 8,0], while in the control one — 1,8 ng/ml [0,8; 3,5] (p=0,0091).Conclusion. Patients with NSTEMI after COVID-19 were significantly younger compared to patients without a history of COVID-19. They had less common exertional angina prior to MI, while C-reactive protein and troponin I levels were significantly higher than in the control group. In addition, in NSTEMI patients after COVID-19, the estimated pulmonary artery systolic pressure was significantly higher compared to patients without a history of COVID-19.https://cardiovascular.elpub.ru/jour/article/view/3062covid-19post-covid-19 syndromemyocardial infarction |
| spellingShingle | M. G. Chashchin A. Yu. Gorshkov O. M. Drapkina I. V. Kositsyna A. V. Golubev N. I. Chaus S. N. Perekhodov Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19 Кардиоваскулярная терапия и профилактика covid-19 post-covid-19 syndrome myocardial infarction |
| title | Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19 |
| title_full | Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19 |
| title_fullStr | Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19 |
| title_full_unstemmed | Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19 |
| title_short | Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19 |
| title_sort | clinical and anamnestic characteristics of patients with non st elevation myocardial infarction after covid 19 |
| topic | covid-19 post-covid-19 syndrome myocardial infarction |
| url | https://cardiovascular.elpub.ru/jour/article/view/3062 |
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