Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis
Purpose: The aim of this study was to evaluate the relationship between autoimmune liver diseases and esophageal motor disorders (EMD). Materials and Methods: 63 patients diagnosed with primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) and followe...
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| Format: | Article |
| Language: | English |
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Cukurova University
2022-03-01
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| Series: | Cukurova Medical Journal |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1932284 |
| _version_ | 1797915582276829184 |
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| author | Sabite Kacar Volkan Gökbulut Ömer Öztürk Meral Akdoğan Kayhan Mustafa Kaplan Hale Sümer Püren Gökbulut Derya Arı Dilara Turan Gökçe |
| author_facet | Sabite Kacar Volkan Gökbulut Ömer Öztürk Meral Akdoğan Kayhan Mustafa Kaplan Hale Sümer Püren Gökbulut Derya Arı Dilara Turan Gökçe |
| author_sort | Sabite Kacar |
| collection | DOAJ |
| description | Purpose: The aim of this study was to evaluate the relationship between autoimmune liver diseases and esophageal motor disorders (EMD).
Materials and Methods: 63 patients diagnosed with primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) and followed up in our hospital were included in the study. The control group consisted of 33 patients. Upper gastrointestinal endoscopy, esophageal motility study and pH meter tests were performed on all participants.
Results: Of the 63 patients included in the study 49.2% of the patients, EMD was detected while 31.7% of them had pathology in the pH meter. The rates of EMD of patients with PBC, PSC and AIH were 50%, 63.6%, and 42.9%, respectively while the pathology rates of the pH meter were found as 25%, 54.5%, and 28.6%, respectively. Statistically significant difference was found between autoimmune liver disease and control group in terms of esophageal motor diseases. As a result of manometric examination, median lower esophageal sphincter resting pressure was significantly lower in autoimmune liver patients compared to the control group.
Conclusion: Our study presents that EMD is common in patients with PBC, PSC, and AIH, and that the presence of cirrhosis has no impact on the development of EMD. |
| first_indexed | 2024-04-10T12:43:51Z |
| format | Article |
| id | doaj.art-4f01947864544315b1a590d61f7b17d0 |
| institution | Directory Open Access Journal |
| issn | 2602-3040 |
| language | English |
| last_indexed | 2024-04-10T12:43:51Z |
| publishDate | 2022-03-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Cukurova Medical Journal |
| spelling | doaj.art-4f01947864544315b1a590d61f7b17d02023-02-15T16:14:10ZengCukurova UniversityCukurova Medical Journal2602-30402022-03-01471212810.17826/cumj.98455148Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitisSabite Kacar0Volkan Gökbulut1Ömer Öztürk2Meral Akdoğan Kayhan3Mustafa Kaplan4Hale Sümer5Püren Gökbulut6Derya Arı7Dilara Turan Gökçe8SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜKayseri Memorial HastanesiANKARA UNIVERSITY, ANKARA FACULTY OF MEDICINEAnkara Eğitim ve Araştırma HastanesiSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ANKARA ŞEHİR SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜPurpose: The aim of this study was to evaluate the relationship between autoimmune liver diseases and esophageal motor disorders (EMD). Materials and Methods: 63 patients diagnosed with primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) and followed up in our hospital were included in the study. The control group consisted of 33 patients. Upper gastrointestinal endoscopy, esophageal motility study and pH meter tests were performed on all participants. Results: Of the 63 patients included in the study 49.2% of the patients, EMD was detected while 31.7% of them had pathology in the pH meter. The rates of EMD of patients with PBC, PSC and AIH were 50%, 63.6%, and 42.9%, respectively while the pathology rates of the pH meter were found as 25%, 54.5%, and 28.6%, respectively. Statistically significant difference was found between autoimmune liver disease and control group in terms of esophageal motor diseases. As a result of manometric examination, median lower esophageal sphincter resting pressure was significantly lower in autoimmune liver patients compared to the control group. Conclusion: Our study presents that EMD is common in patients with PBC, PSC, and AIH, and that the presence of cirrhosis has no impact on the development of EMD.https://dergipark.org.tr/tr/download/article-file/1932284primer biliyer kolanjitprimer sklerozan kolanjitotoimmün hepatitözofagus motilite bozukluğuprimary biliary cholangitisprimary sclerosing cholangitisautoimmune hepatitisesophageal motility disorder |
| spellingShingle | Sabite Kacar Volkan Gökbulut Ömer Öztürk Meral Akdoğan Kayhan Mustafa Kaplan Hale Sümer Püren Gökbulut Derya Arı Dilara Turan Gökçe Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis Cukurova Medical Journal primer biliyer kolanjit primer sklerozan kolanjit otoimmün hepatit özofagus motilite bozukluğu primary biliary cholangitis primary sclerosing cholangitis autoimmune hepatitis esophageal motility disorder |
| title | Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis |
| title_full | Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis |
| title_fullStr | Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis |
| title_full_unstemmed | Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis |
| title_short | Evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis, primary sclerosing cholangitis and autoimmune hepatitis |
| title_sort | evaluation of esophageal motor functions in patients diagnosed with primary biliary cholangitis primary sclerosing cholangitis and autoimmune hepatitis |
| topic | primer biliyer kolanjit primer sklerozan kolanjit otoimmün hepatit özofagus motilite bozukluğu primary biliary cholangitis primary sclerosing cholangitis autoimmune hepatitis esophageal motility disorder |
| url | https://dergipark.org.tr/tr/download/article-file/1932284 |
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