Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon
ABSTRACT: Intracranial tumors occurring in specific brain regions, such as the cerebellopontine angle, may be associated with cranial nerve dysfunction and dysphagia in humans and animals. Although dysphagia is a known risk factor for pneumonia, only postoperative pneumonia has been investigated in...
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| Format: | Article |
| Language: | English |
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Colégio Brasileiro de Patologia Animal (CBPA)
2023-04-01
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| Series: | Pesquisa Veterinária Brasileira |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2023000100409&tlng=en |
| _version_ | 1797839793321672704 |
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| author | Bruno A. Almeida Luan C. Henker Matheus V. Bianchi Saulo P. Pavarini Luciana Sonne David Driemeier |
| author_facet | Bruno A. Almeida Luan C. Henker Matheus V. Bianchi Saulo P. Pavarini Luciana Sonne David Driemeier |
| author_sort | Bruno A. Almeida |
| collection | DOAJ |
| description | ABSTRACT: Intracranial tumors occurring in specific brain regions, such as the cerebellopontine angle, may be associated with cranial nerve dysfunction and dysphagia in humans and animals. Although dysphagia is a known risk factor for pneumonia, only postoperative pneumonia has been investigated in veterinary medicine. This study aimed to describe the clinical and pathological features of dogs with untreated intracranial meningiomas and concomitant pneumonia. Data from post-mortem examination registries from 2011 to 2021 were used (n=23). The frequency of pneumonia and other characteristics were compared between dogs with meningiomas in the ventral rhombencephalon region (VR group; n=13) and those with meningiomas in other intracranial sites (OIS group; n=10). The frequency of pneumonia was higher in the VR group than in the OIS group (n=5 vs. n=0; P=0.039). Plaque-like lesions were also more common in the VR group than in the OIS group (P=0.012). Dogs with concomitant pneumonia had cerebellopontine angle (n=3) and basilar meningiomas (n=2), mainly plaque-like lesions extending to or from other brain areas. In dogs with concomitant pneumonia, meningiomas had invasive (n=5) and compressive (n=3) growth behaviors and nerve roots involved in the swallowing process were frequently affected. Microscopically, these meningiomas were classified as atypical (n=4) and meningiomas (n=1). The reported clinical signs included anorexia (n=3), adipsia (n=1), and dysphagia (n=1). Our findings suggest untreated dogs with ventral rhombencephalon meningiomas may develop cranial nerve damage and aspiration pneumonia. |
| first_indexed | 2024-04-09T16:03:54Z |
| format | Article |
| id | doaj.art-4f057bafc4b7470cabb568a5e31ac93c |
| institution | Directory Open Access Journal |
| issn | 1678-5150 |
| language | English |
| last_indexed | 2024-04-09T16:03:54Z |
| publishDate | 2023-04-01 |
| publisher | Colégio Brasileiro de Patologia Animal (CBPA) |
| record_format | Article |
| series | Pesquisa Veterinária Brasileira |
| spelling | doaj.art-4f057bafc4b7470cabb568a5e31ac93c2023-04-25T07:31:29ZengColégio Brasileiro de Patologia Animal (CBPA)Pesquisa Veterinária Brasileira1678-51502023-04-014310.1590/1678-5150-pvb-7114Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalonBruno A. Almeidahttps://orcid.org/0000-0001-5859-6335Luan C. Henkerhttps://orcid.org/0000-0001-6556-2010Matheus V. Bianchihttps://orcid.org/0000-0002-3951-0038Saulo P. Pavarinihttps://orcid.org/0000-0001-8980-6294Luciana Sonnehttps://orcid.org/0000-0003-3101-8134David Driemeierhttps://orcid.org/0000-0003-3766-0654ABSTRACT: Intracranial tumors occurring in specific brain regions, such as the cerebellopontine angle, may be associated with cranial nerve dysfunction and dysphagia in humans and animals. Although dysphagia is a known risk factor for pneumonia, only postoperative pneumonia has been investigated in veterinary medicine. This study aimed to describe the clinical and pathological features of dogs with untreated intracranial meningiomas and concomitant pneumonia. Data from post-mortem examination registries from 2011 to 2021 were used (n=23). The frequency of pneumonia and other characteristics were compared between dogs with meningiomas in the ventral rhombencephalon region (VR group; n=13) and those with meningiomas in other intracranial sites (OIS group; n=10). The frequency of pneumonia was higher in the VR group than in the OIS group (n=5 vs. n=0; P=0.039). Plaque-like lesions were also more common in the VR group than in the OIS group (P=0.012). Dogs with concomitant pneumonia had cerebellopontine angle (n=3) and basilar meningiomas (n=2), mainly plaque-like lesions extending to or from other brain areas. In dogs with concomitant pneumonia, meningiomas had invasive (n=5) and compressive (n=3) growth behaviors and nerve roots involved in the swallowing process were frequently affected. Microscopically, these meningiomas were classified as atypical (n=4) and meningiomas (n=1). The reported clinical signs included anorexia (n=3), adipsia (n=1), and dysphagia (n=1). Our findings suggest untreated dogs with ventral rhombencephalon meningiomas may develop cranial nerve damage and aspiration pneumonia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2023000100409&tlng=enCaninedogspneumoniameningiomaventral rhombencephaloncranial nervesdysphagianeuropathology |
| spellingShingle | Bruno A. Almeida Luan C. Henker Matheus V. Bianchi Saulo P. Pavarini Luciana Sonne David Driemeier Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon Pesquisa Veterinária Brasileira Canine dogs pneumonia meningioma ventral rhombencephalon cranial nerves dysphagia neuropathology |
| title | Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon |
| title_full | Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon |
| title_fullStr | Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon |
| title_full_unstemmed | Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon |
| title_short | Increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon |
| title_sort | increased frequency of pneumonia in dogs with meningioma in ventral rhombencephalon |
| topic | Canine dogs pneumonia meningioma ventral rhombencephalon cranial nerves dysphagia neuropathology |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2023000100409&tlng=en |
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