Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review

Abstract Inferior vena cava thrombosis (IVCT) is rare and can be under-recognized. However, the associated complications and mortality may be severe. We report the first case series of IVCT observed in Taiwan with a brief literature review. Eight Taiwanese patients with IVCT between May 2012 and Dec...

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Main Authors: Hsuan-Yu Lin, Ching-Yeh Lin, Ming-Ching Shen
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Thrombosis Journal
Subjects:
Online Access:https://doi.org/10.1186/s12959-021-00296-5
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author Hsuan-Yu Lin
Ching-Yeh Lin
Ming-Ching Shen
author_facet Hsuan-Yu Lin
Ching-Yeh Lin
Ming-Ching Shen
author_sort Hsuan-Yu Lin
collection DOAJ
description Abstract Inferior vena cava thrombosis (IVCT) is rare and can be under-recognized. However, the associated complications and mortality may be severe. We report the first case series of IVCT observed in Taiwan with a brief literature review. Eight Taiwanese patients with IVCT between May 2012 and December 2019 were enrolled in this study. Deep venous thrombosis (DVT, 8/8) and pulmonary embolism (5/8) were reported. Various risk factors were identified, including an unretrieved inferior vena cava (IVC) filter, pregnancy, surgery, presence of lupus of anticoagulants, essential thrombocythemia, antithrombin deficiency, and hemoglobin H disease. Of note, four of our patients experienced complete IVC thrombosis with bilateral lower extremity swelling (due to DVT) and abdominal wall superficial venous dilatation, while four other patients presented with partial IVCT and unilateral DVT. The etiology, clinical characteristics, presentations, diagnosis, and treatment of IVCT were reviewed.
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spelling doaj.art-4f08111412e946aaa259a6afdc2d0e482022-12-21T22:05:05ZengBMCThrombosis Journal1477-95602021-06-0119111110.1186/s12959-021-00296-5Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature reviewHsuan-Yu Lin0Ching-Yeh Lin1Ming-Ching Shen2Division of Hematology/Oncology, Changhua Christian HospitalDivision of Hematology/Oncology, Changhua Christian HospitalDivision of Hematology/Oncology, Changhua Christian HospitalAbstract Inferior vena cava thrombosis (IVCT) is rare and can be under-recognized. However, the associated complications and mortality may be severe. We report the first case series of IVCT observed in Taiwan with a brief literature review. Eight Taiwanese patients with IVCT between May 2012 and December 2019 were enrolled in this study. Deep venous thrombosis (DVT, 8/8) and pulmonary embolism (5/8) were reported. Various risk factors were identified, including an unretrieved inferior vena cava (IVC) filter, pregnancy, surgery, presence of lupus of anticoagulants, essential thrombocythemia, antithrombin deficiency, and hemoglobin H disease. Of note, four of our patients experienced complete IVC thrombosis with bilateral lower extremity swelling (due to DVT) and abdominal wall superficial venous dilatation, while four other patients presented with partial IVCT and unilateral DVT. The etiology, clinical characteristics, presentations, diagnosis, and treatment of IVCT were reviewed.https://doi.org/10.1186/s12959-021-00296-5Inferior vena cavaVenous thromboembolismPulmonary embolismTaiwanVena cava filtersPost-thrombotic syndrome
spellingShingle Hsuan-Yu Lin
Ching-Yeh Lin
Ming-Ching Shen
Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review
Thrombosis Journal
Inferior vena cava
Venous thromboembolism
Pulmonary embolism
Taiwan
Vena cava filters
Post-thrombotic syndrome
title Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review
title_full Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review
title_fullStr Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review
title_full_unstemmed Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review
title_short Review article inferior vena cava thrombosis: a case series of patients observed in Taiwan and literature review
title_sort review article inferior vena cava thrombosis a case series of patients observed in taiwan and literature review
topic Inferior vena cava
Venous thromboembolism
Pulmonary embolism
Taiwan
Vena cava filters
Post-thrombotic syndrome
url https://doi.org/10.1186/s12959-021-00296-5
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