Treponema Pallidum epidermotropism in nodular secondary syphilis
Nodular secondary syphilis results from the hematogenous and lymphatic dissemination of spirochetes. Clinically, the lesions appear as partially infiltrated plaques or red-violaceous nodules, which can be solitary or multiple. Several hypotheses have been put forward to explain the formation of thes...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2018;volume=63;issue=6;spage=509;epage=511;aulast=Magdaleno-Tapial |
| _version_ | 1819156518198575104 |
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| author | Jorge Magdaleno-Tapial Cristian Valenzuela-Oñate José María Ortiz-Salvador Pablo Hernández-Bel Víctor Alegre-De Miquel |
| author_facet | Jorge Magdaleno-Tapial Cristian Valenzuela-Oñate José María Ortiz-Salvador Pablo Hernández-Bel Víctor Alegre-De Miquel |
| author_sort | Jorge Magdaleno-Tapial |
| collection | DOAJ |
| description | Nodular secondary syphilis results from the hematogenous and lymphatic dissemination of spirochetes. Clinically, the lesions appear as partially infiltrated plaques or red-violaceous nodules, which can be solitary or multiple. Several hypotheses have been put forward to explain the formation of these infiltrated or granulomatous lesions. Among the most accepted are the specific hypersensitivity reactions to Treponema pallidum or the lenghty duration of the disease. We present a case of nodular syphilis where immunohistochemistry revealed the presence of multiple spirochetes invading the epidermis. |
| first_indexed | 2024-12-22T15:54:01Z |
| format | Article |
| id | doaj.art-4f09f730247846e0afd17970757e8f81 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-22T15:54:01Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-4f09f730247846e0afd17970757e8f812022-12-21T18:20:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112018-01-0163650951110.4103/ijd.IJD_232_18Treponema Pallidum epidermotropism in nodular secondary syphilisJorge Magdaleno-TapialCristian Valenzuela-OñateJosé María Ortiz-SalvadorPablo Hernández-BelVíctor Alegre-De MiquelNodular secondary syphilis results from the hematogenous and lymphatic dissemination of spirochetes. Clinically, the lesions appear as partially infiltrated plaques or red-violaceous nodules, which can be solitary or multiple. Several hypotheses have been put forward to explain the formation of these infiltrated or granulomatous lesions. Among the most accepted are the specific hypersensitivity reactions to Treponema pallidum or the lenghty duration of the disease. We present a case of nodular syphilis where immunohistochemistry revealed the presence of multiple spirochetes invading the epidermis.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2018;volume=63;issue=6;spage=509;epage=511;aulast=Magdaleno-TapialEpidermotropismgranulomatous lesionnodular syphilistreponema pallidum |
| spellingShingle | Jorge Magdaleno-Tapial Cristian Valenzuela-Oñate José María Ortiz-Salvador Pablo Hernández-Bel Víctor Alegre-De Miquel Treponema Pallidum epidermotropism in nodular secondary syphilis Indian Journal of Dermatology Epidermotropism granulomatous lesion nodular syphilis treponema pallidum |
| title | Treponema Pallidum epidermotropism in nodular secondary syphilis |
| title_full | Treponema Pallidum epidermotropism in nodular secondary syphilis |
| title_fullStr | Treponema Pallidum epidermotropism in nodular secondary syphilis |
| title_full_unstemmed | Treponema Pallidum epidermotropism in nodular secondary syphilis |
| title_short | Treponema Pallidum epidermotropism in nodular secondary syphilis |
| title_sort | treponema pallidum epidermotropism in nodular secondary syphilis |
| topic | Epidermotropism granulomatous lesion nodular syphilis treponema pallidum |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2018;volume=63;issue=6;spage=509;epage=511;aulast=Magdaleno-Tapial |
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