Sendai virus-based immunoadjuvant in hydrogel vaccine intensity-modulated dendritic cells activation for suppressing tumorigenesis

Sendai virus-based immunoadjuvant in hydrogel vaccine intensity-modulated dendritic cells activation for suppressing tumorigenesis

The conventional immunoadjuvants in vaccine have weak effect on stimulating antigen presentation and activating anti-tumor immunity. Unexpectedly, we discovered that non-pathogenic Sendai virus (SeV) could activate antigen-presenting cells (APCs) represented by dendritic cells (DCs). Here, we design...

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Bibliographic Details
Main Authors: Bin Zheng, Wenchang Peng, Lin Gan, Mingming Guo, Shuchao Wang, Xiao-Dong Zhang, Dong Ming
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-11-01
Series:Bioactive Materials
Subjects:
Hydrogel vaccine
Sendai virus (SeV)
Immunoadjuvant
Dendritic cells
Immunoprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21001596

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