Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019
ObjectiveFalls in older people have become a major public health, economic and societal problem. Osteoporosis predisposes older adults to high risk of falls, which were the most common outcome attributable to low bone mineral density (LBMD). In this study, we analyze the long-term trends in falls bu...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-06-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1204497/full |
| _version_ | 1797793648738304000 |
|---|---|
| author | Yali Fu Yali Fu Yali Fu Lei Ba Lei Ba Lei Ba Nianqing Lü Nianqing Lü Nianqing Lü Huafeng Yang Xin Hong Jinyi Zhou Zhiming Sun Zhiming Sun Zhiming Sun |
| author_facet | Yali Fu Yali Fu Yali Fu Lei Ba Lei Ba Lei Ba Nianqing Lü Nianqing Lü Nianqing Lü Huafeng Yang Xin Hong Jinyi Zhou Zhiming Sun Zhiming Sun Zhiming Sun |
| author_sort | Yali Fu |
| collection | DOAJ |
| description | ObjectiveFalls in older people have become a major public health, economic and societal problem. Osteoporosis predisposes older adults to high risk of falls, which were the most common outcome attributable to low bone mineral density (LBMD). In this study, we analyze the long-term trends in falls burden attributable to LBMD among people aged 60 years and over from 1990 to 2019, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019).MethodsData from GBD 2019 were used to assess the long-term trends in mortality and disability-adjusted life-year (DALY) rates by Joinpoint regression. The age-period-cohort (APC) model was used to evaluate the effects of age, period and cohort on mortality rate of falls attributable to LBMD.ResultsThe mortality and DALYs rates of falls attributable to LBMD among people aged 60 years and over increased from 1990 to 2019, with average annual percentage changes (AAPCs) of 1.74% (95% CI: −1.47 to 2.01%) and 0.99% (95% CI: 0.80–1.19%), respectively. APC analysis revealed that the mortality rate due to LBMD significantly increased among the older people over the age of 75 years. The risk of falls mortality due to LBMD during the period of 1990–2019 initially declined but later elevated. An overall increasing risk for falls death attributable to LBMD was presented across birth cohorts, but in cohorts born after 1930, the upward trend has slowed down. The overall net drift per year attributable to LBMD was above 0. The corresponding results showed that the negative impact of period and cohort effects among males was more pronounced than those among females.ConclusionsFalls attributable to LBMD remain an ongoing health burden in the older people in China, and the mortality has been on the rise from 1990 to 2019, especially among the older people aged 80+ years group. The prevention and treatment of LBMD should be emphasized, especially among males and oldest-old people. Furthermore, there is an urgent need to strengthen the implementation of system-wide, integrated and effective public health policies and other health interventions in China. |
| first_indexed | 2024-03-13T02:51:23Z |
| format | Article |
| id | doaj.art-4f0df05b0ba346d294356d7a8610da92 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-13T02:51:23Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-4f0df05b0ba346d294356d7a8610da922023-06-28T11:57:53ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-06-011110.3389/fpubh.2023.12044971204497Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019Yali Fu0Yali Fu1Yali Fu2Lei Ba3Lei Ba4Lei Ba5Nianqing Lü6Nianqing Lü7Nianqing Lü8Huafeng Yang9Xin Hong10Jinyi Zhou11Zhiming Sun12Zhiming Sun13Zhiming Sun14Jiangsu Health Development Research Center, Nanjing, Jiangsu, ChinaNational Health Commission Key Laboratory of Contraceptives Adverse Reaction Surveillance, Nanjing, Jiangsu, ChinaJiangsu Provincial Medical Key Laboratory of Fertility Protection and Health Technology Assessment, Nanjing, Jiangsu, ChinaJiangsu Health Development Research Center, Nanjing, Jiangsu, ChinaNational Health Commission Key Laboratory of Contraceptives Adverse Reaction Surveillance, Nanjing, Jiangsu, ChinaJiangsu Provincial Medical Key Laboratory of Fertility Protection and Health Technology Assessment, Nanjing, Jiangsu, ChinaJiangsu Health Development Research Center, Nanjing, Jiangsu, ChinaNational Health Commission Key Laboratory of Contraceptives Adverse Reaction Surveillance, Nanjing, Jiangsu, ChinaJiangsu Provincial Medical Key Laboratory of Fertility Protection and Health Technology Assessment, Nanjing, Jiangsu, ChinaNanjing Municipal Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaNanjing Municipal Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaJiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, ChinaJiangsu Health Development Research Center, Nanjing, Jiangsu, ChinaNational Health Commission Key Laboratory of Contraceptives Adverse Reaction Surveillance, Nanjing, Jiangsu, ChinaJiangsu Provincial Medical Key Laboratory of Fertility Protection and Health Technology Assessment, Nanjing, Jiangsu, ChinaObjectiveFalls in older people have become a major public health, economic and societal problem. Osteoporosis predisposes older adults to high risk of falls, which were the most common outcome attributable to low bone mineral density (LBMD). In this study, we analyze the long-term trends in falls burden attributable to LBMD among people aged 60 years and over from 1990 to 2019, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019).MethodsData from GBD 2019 were used to assess the long-term trends in mortality and disability-adjusted life-year (DALY) rates by Joinpoint regression. The age-period-cohort (APC) model was used to evaluate the effects of age, period and cohort on mortality rate of falls attributable to LBMD.ResultsThe mortality and DALYs rates of falls attributable to LBMD among people aged 60 years and over increased from 1990 to 2019, with average annual percentage changes (AAPCs) of 1.74% (95% CI: −1.47 to 2.01%) and 0.99% (95% CI: 0.80–1.19%), respectively. APC analysis revealed that the mortality rate due to LBMD significantly increased among the older people over the age of 75 years. The risk of falls mortality due to LBMD during the period of 1990–2019 initially declined but later elevated. An overall increasing risk for falls death attributable to LBMD was presented across birth cohorts, but in cohorts born after 1930, the upward trend has slowed down. The overall net drift per year attributable to LBMD was above 0. The corresponding results showed that the negative impact of period and cohort effects among males was more pronounced than those among females.ConclusionsFalls attributable to LBMD remain an ongoing health burden in the older people in China, and the mortality has been on the rise from 1990 to 2019, especially among the older people aged 80+ years group. The prevention and treatment of LBMD should be emphasized, especially among males and oldest-old people. Furthermore, there is an urgent need to strengthen the implementation of system-wide, integrated and effective public health policies and other health interventions in China.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1204497/fullfallslow bone mineral densityosteoporosisage-period-cohort analysisburden |
| spellingShingle | Yali Fu Yali Fu Yali Fu Lei Ba Lei Ba Lei Ba Nianqing Lü Nianqing Lü Nianqing Lü Huafeng Yang Xin Hong Jinyi Zhou Zhiming Sun Zhiming Sun Zhiming Sun Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019 Frontiers in Public Health falls low bone mineral density osteoporosis age-period-cohort analysis burden |
| title | Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019 |
| title_full | Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019 |
| title_fullStr | Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019 |
| title_full_unstemmed | Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019 |
| title_short | Burden of falls attributable to low bone mineral density among people aged 60 years and over in China from 1990 to 2019 |
| title_sort | burden of falls attributable to low bone mineral density among people aged 60 years and over in china from 1990 to 2019 |
| topic | falls low bone mineral density osteoporosis age-period-cohort analysis burden |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1204497/full |
| work_keys_str_mv | AT yalifu burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT yalifu burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT yalifu burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT leiba burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT leiba burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT leiba burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT nianqinglu burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT nianqinglu burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT nianqinglu burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT huafengyang burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT xinhong burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT jinyizhou burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT zhimingsun burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT zhimingsun burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 AT zhimingsun burdenoffallsattributabletolowbonemineraldensityamongpeopleaged60yearsandoverinchinafrom1990to2019 |