The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans

The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans

Bone production, maintenance, and modeling are a well-balanced process involving mineralization by osteoblasts and resorption by osteoclasts. Sex steroid hormones, including their conjugated forms, contribute majorly to maintaining this balance. Recently, variants in the SLC22A9 gene have been assoc...

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Bibliographic Details
Main Authors: Anne T. Nies, Stefan Weiss, Elke Schaeffeler, Anke Hannemann, Uwe Völker, Henri Wallaschofski, Matthias Schwab
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Endocrinology
Subjects:
estrone sulfate transporter
SLC22A9
osteoporosis
human association studies
sex steroids
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00532/full

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