Age-related differences in affective behaviors in mice: possible role of prefrontal cortical-hippocampal functional connectivity and metabolomic profiles

Age-related differences in affective behaviors in mice: possible role of prefrontal cortical-hippocampal functional connectivity and metabolomic profiles

IntroductionThe differential expression of emotional reactivity from early to late adulthood may involve maturation of prefrontal cortical responses to negative valence stimuli. In mice, age-related changes in affective behaviors have been reported, but the functional neural circuitry warrants furth...

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Bibliographic Details
Main Authors:	Marcelo Febo, Rohit Mahar, Nicholas A. Rodriguez, Joy Buraima, Marjory Pompilus, Aeja M. Pinto, Matteo M. Grudny, Adriaan W. Bruijnzeel, Matthew E. Merritt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Aging Neuroscience
Subjects:	aging brain maturation fMRI fear conditioning locomotor activity functional connectivity
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2024.1356086/full

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