Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.
Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...
Những tác giả chính: | , , , , , , , |
---|---|
Định dạng: | Bài viết |
Ngôn ngữ: | English |
Được phát hành: |
Public Library of Science (PLoS)
2012-01-01
|
Loạt: | PLoS ONE |
Truy cập trực tuyến: | http://europepmc.org/articles/PMC3431405?pdf=render |