Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...

Full description

Bibliographic Details
Main Authors: Jin Yang, Matthew C Naumann, Yi-Ting Tsai, Joaquin Tosi, Deniz Erol, Chyuan-Sheng Lin, Richard J Davis, Stephen H Tsang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3431405?pdf=render

Similar Items

Similar Items