Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.
Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...
المؤلفون الرئيسيون: | Jin Yang, Matthew C Naumann, Yi-Ting Tsai, Joaquin Tosi, Deniz Erol, Chyuan-Sheng Lin, Richard J Davis, Stephen H Tsang |
---|---|
التنسيق: | مقال |
اللغة: | English |
منشور في: |
Public Library of Science (PLoS)
2012-01-01
|
سلاسل: | PLoS ONE |
الوصول للمادة أونلاين: | http://europepmc.org/articles/PMC3431405?pdf=render |
مواد مشابهة
-
Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells
حسب: Saeed Khalili, وآخرون
منشور في: (2018-12-01) -
Multiphoton response of retinal rod photoreceptors
حسب: Vasilios Alexiades, وآخرون
منشور في: (2007-02-01) -
Vigabatrin Associated Retinal Pathology
حسب: J Gordon Millichap
منشور في: (2002-01-01) -
Irradiance encoding in the suprachiasmatic nuclei by rod and cone photoreceptors.
حسب: van Diepen, H, وآخرون
منشور في: (2013) -
Adaptation memory in photoreceptors: different mechanisms in rods and cones
حسب: Darya A. Nikolaeva, وآخرون
منشور في: (2023-04-01)