Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Jin Yang, Matthew C Naumann, Yi-Ting Tsai, Joaquin Tosi, Deniz Erol, Chyuan-Sheng Lin, Richard J Davis, Stephen H Tsang
स्वरूप:	लेख
भाषा:	English
प्रकाशित:	Public Library of Science (PLoS) 2012-01-01
श्रृंखला:	PLoS ONE
ऑनलाइन पहुंच:	http://europepmc.org/articles/PMC3431405?pdf=render

समान संसाधन

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प्रकाशित: (2018-12-01)

Multiphoton response of retinal rod photoreceptors
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प्रकाशित: (2007-02-01)

Vigabatrin Associated Retinal Pathology
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प्रकाशित: (2002-01-01)

Irradiance encoding in the suprachiasmatic nuclei by rod and cone photoreceptors.
द्वारा: van Diepen, H, और अन्य
प्रकाशित: (2013)

Adaptation memory in photoreceptors: different mechanisms in rods and cones
द्वारा: Darya A. Nikolaeva, और अन्य
प्रकाशित: (2023-04-01)

Neuroprotection of cone photoreceptors in retinitis pigmentosa
द्वारा: Lipinski, D, और अन्य
प्रकाशित: (2013)

Oncostatin M protects rod and cone photoreceptors and promotes regeneration of cone outer segment in a rat model of retinal degeneration.
द्वारा: Xin Xia, और अन्य
प्रकाशित: (2011-03-01)

Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.
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Metabolic rescue of cone photoreceptors in retinitis pigmentosa
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प्रकाशित: (2021-01-01)

Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa
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प्रकाशित: (2017-09-01)

Pias3 is necessary for dorso-ventral patterning and visual response of retinal cones but is not required for rod photoreceptor differentiation
द्वारा: Christie K. Campla, और अन्य
प्रकाशित: (2017-06-01)

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प्रकाशित: (1999-05-01)

Robust cone-mediated signaling persists late into rod photoreceptor degeneration
द्वारा: Miranda L Scalabrino, और अन्य
प्रकाशित: (2022-08-01)

Childhood-onset genetic cone-rod photoreceptor diseases and underlying pathobiology
द्वारा: Alexandra V. Garafalo, और अन्य
प्रकाशित: (2021-01-01)

The Vigabatrin Induced Retinal Toxicity is Associated with Photopic Exposure and Taurine Deficiency: An In Vivo Study
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प्रकाशित: (2016-12-01)

Universality of Form: The Case of Retinal Cone Photoreceptor Mosaics
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प्रकाशित: (2023-05-01)

gdf6a is required for cone photoreceptor subtype differentiation and for the actions of tbx2b in determining rod versus cone photoreceptor fate.
द्वारा: Michèle G Duval, और अन्य
प्रकाशित: (2014-01-01)

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द्वारा: Nan-Kai Wang, और अन्य
प्रकाशित: (2023-06-01)

Analysis of rod/cone gap junctions from the reconstruction of mouse photoreceptor terminals
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प्रकाशित: (2022-04-01)

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द्वारा: Martin-Paul Agbaga, और अन्य
प्रकाशित: (2018-09-01)

Non-linearities in the Rod and Cone Photoreceptor Inputs to the Afferent Pupil Light Response
द्वारा: Pablo Alejandro Barrionuevo, और अन्य
प्रकाशित: (2018-12-01)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
द्वारा: Sang Joon Lee, और अन्य
प्रकाशित: (2025-01-01)

Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa
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Investigations Into Bioenergetic Neuroprotection of Cone Photoreceptors: Relevance to Retinitis Pigmentosa
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प्रकाशित: (2019-11-01)

Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa.
द्वारा: Andrew Vargas, और अन्य
प्रकाशित: (2017-01-01)

A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
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प्रकाशित: (2005-08-01)

A Hybrid Photoreceptor Expressing Both Rod and Cone Genes in a Mouse Model of Enhanced S-Cone Syndrome.
प्रकाशित: (2005-08-01)

Modeling rod and cone photoreceptor cell survival in vivo using optical coherence tomography
द्वारा: S. Scott Whitmore, और अन्य
प्रकाशित: (2023-04-01)

Functional analysis of Samd11, a retinal photoreceptor PRC1 component, in establishing rod photoreceptor identity
द्वारा: Shun Kubo, और अन्य
प्रकाशित: (2021-02-01)

Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases.
द्वारा: Sunil K Parapuram, और अन्य
प्रकाशित: (2010-11-01)

Correction: A Hybrid Photoreceptor Expressing Both Rod and Cone Genes in a Mouse Model of Enhanced S-Cone Syndrome
प्रकाशित: (2008-01-01)

Correction: A Hybrid Photoreceptor Expressing Both Rod and Cone Genes in a Mouse Model of Enhanced S-Cone Syndrome.
द्वारा: Joseph C Corbo, और अन्य
प्रकाशित: (2008-01-01)

Mouse ganglion-cell photoreceptors are driven by the most sensitive rod pathway and by both types of cones.
द्वारा: Shijun Weng, और अन्य
प्रकाशित: (2013-01-01)

Development and degeneration of cone bipolar cells are independent of cone photoreceptors in a mouse model of retinitis pigmentosa.
द्वारा: Miao Chen, और अन्य
प्रकाशित: (2012-01-01)

A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors
द्वारा: Abirami Santhanam, और अन्य
प्रकाशित: (2020-10-01)

Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.
द्वारा: Hornan, D, और अन्य
प्रकाशित: (2007)

Effect of Direct Current Electric Fields on Cone Like Retinal Photoreceptor Cells
द्वारा: Juliana Guerra-Hühne, और अन्य
प्रकाशित: (2022-09-01)

A positive feedback synapse from retinal horizontal cells to cone photoreceptors.
द्वारा: Skyler L Jackman, और अन्य
प्रकाशित: (2011-05-01)