Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...

Повний опис

Бібліографічні деталі
Автори: Jin Yang, Matthew C Naumann, Yi-Ting Tsai, Joaquin Tosi, Deniz Erol, Chyuan-Sheng Lin, Richard J Davis, Stephen H Tsang
Формат: Стаття
Мова:English
Опубліковано: Public Library of Science (PLoS) 2012-01-01
Серія:PLoS ONE
Онлайн доступ:http://europepmc.org/articles/PMC3431405?pdf=render

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