Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jin Yang, Matthew C Naumann, Yi-Ting Tsai, Joaquin Tosi, Deniz Erol, Chyuan-Sheng Lin, Richard J Davis, Stephen H Tsang
التنسيق: مقال
اللغة:English
منشور في: Public Library of Science (PLoS) 2012-01-01
سلاسل:PLoS ONE
الوصول للمادة أونلاين:http://europepmc.org/articles/PMC3431405?pdf=render