Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.
Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Sprog: | English |
| Udgivet: |
Public Library of Science (PLoS)
2012-01-01
|
| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC3431405?pdf=render |