Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.

Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Jin Yang, Matthew C Naumann, Yi-Ting Tsai, Joaquin Tosi, Deniz Erol, Chyuan-Sheng Lin, Richard J Davis, Stephen H Tsang
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Public Library of Science (PLoS) 2012-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3431405?pdf=render