Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.
Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...
| Հիմնական հեղինակներ: | , , , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Public Library of Science (PLoS)
2012-01-01
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| Շարք: | PLoS ONE |
| Առցանց հասանելիություն: | http://europepmc.org/articles/PMC3431405?pdf=render |