Vigabatrin-induced retinal toxicity is partially mediated by signaling in rod and cone photoreceptors.
Vigabatrin (VGB) is a commonly prescribed antiepileptic drug designed to inhibit GABA-transaminase, effectively halting seizures. Unfortunately, VGB treatment is also associated with the highest frequencies of peripheral visual field constriction of any of the antiepileptic drugs and the mechanisms...
主要な著者: | , , , , , , , |
---|---|
フォーマット: | 論文 |
言語: | English |
出版事項: |
Public Library of Science (PLoS)
2012-01-01
|
シリーズ: | PLoS ONE |
オンライン・アクセス: | http://europepmc.org/articles/PMC3431405?pdf=render |