Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations

Abstract Right heart thrombi (RHT) continues to pose a clinical dilemma for multiple specialties and is especially concerning when present with concomitant pulmonary embolism (PE). Patients with PE and RHT are at an increased risk of poor outcomes compared to PE without RHT. Although the exact incid...

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Main Authors: Akhil Khosla, Hamid Mojibian, Roland Assi, Hossam Tantawy, Inderjit Singh, Jeffrey Pollak
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Pulmonary Circulation
Subjects:
Online Access:https://doi.org/10.1002/pul2.12080
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author Akhil Khosla
Hamid Mojibian
Roland Assi
Hossam Tantawy
Inderjit Singh
Jeffrey Pollak
author_facet Akhil Khosla
Hamid Mojibian
Roland Assi
Hossam Tantawy
Inderjit Singh
Jeffrey Pollak
author_sort Akhil Khosla
collection DOAJ
description Abstract Right heart thrombi (RHT) continues to pose a clinical dilemma for multiple specialties and is especially concerning when present with concomitant pulmonary embolism (PE). Patients with PE and RHT are at an increased risk of poor outcomes compared to PE without RHT. Although the exact incidence of RHT is unknown, the increasing use of point‐of‐care ultrasound may lead to an increased detection and frequency of RHT. There are multiple treatment strategies available for RHT, including anticoagulation, systemic thrombolysis, and endovascular and surgical therapies. Given that these treatment strategies involve multiple medical specialties, the management of RHT with concomitant PE can be complex. Currently, there is limited clinical data and guidelines on the treatment and management of RHT. We aim to provide a review on RHT with concomitant PE, including risk stratification, treatment considerations, and our approach to the management of RHT.
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spelling doaj.art-4f18283e955c4ecfbd1f8bd169177e192023-08-09T10:21:08ZengWileyPulmonary Circulation2045-89402022-04-01122n/an/a10.1002/pul2.12080Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerationsAkhil Khosla0Hamid Mojibian1Roland Assi2Hossam Tantawy3Inderjit Singh4Jeffrey Pollak5Department of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine Yale New Haven Hospital New‐Haven Connecticut USADepartment of Radiology and Biomedical Imaging, Section of Vascular and Interventional Radiology Yale University School of Medicine New Haven Connecticut USADivision of Cardiac Surgery Yale University School of Medicine New Haven Connecticut USADepartment of Anesthesiology Yale University School of Medicine New Haven Connecticut USADepartment of Internal Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine Yale New Haven Hospital New‐Haven Connecticut USADepartment of Radiology and Biomedical Imaging, Section of Vascular and Interventional Radiology Yale University School of Medicine New Haven Connecticut USAAbstract Right heart thrombi (RHT) continues to pose a clinical dilemma for multiple specialties and is especially concerning when present with concomitant pulmonary embolism (PE). Patients with PE and RHT are at an increased risk of poor outcomes compared to PE without RHT. Although the exact incidence of RHT is unknown, the increasing use of point‐of‐care ultrasound may lead to an increased detection and frequency of RHT. There are multiple treatment strategies available for RHT, including anticoagulation, systemic thrombolysis, and endovascular and surgical therapies. Given that these treatment strategies involve multiple medical specialties, the management of RHT with concomitant PE can be complex. Currently, there is limited clinical data and guidelines on the treatment and management of RHT. We aim to provide a review on RHT with concomitant PE, including risk stratification, treatment considerations, and our approach to the management of RHT.https://doi.org/10.1002/pul2.12080pulmonary embolism (PE)right heart thrombi (RHT)thrombectomythrombolytic therapy
spellingShingle Akhil Khosla
Hamid Mojibian
Roland Assi
Hossam Tantawy
Inderjit Singh
Jeffrey Pollak
Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations
Pulmonary Circulation
pulmonary embolism (PE)
right heart thrombi (RHT)
thrombectomy
thrombolytic therapy
title Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations
title_full Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations
title_fullStr Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations
title_full_unstemmed Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations
title_short Right heart thrombi (RHT) and clot in transit with concomitant PE management: Approach and considerations
title_sort right heart thrombi rht and clot in transit with concomitant pe management approach and considerations
topic pulmonary embolism (PE)
right heart thrombi (RHT)
thrombectomy
thrombolytic therapy
url https://doi.org/10.1002/pul2.12080
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