The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments

Graphical AbstractPoor environmental conditions combined with continuous unhealthy and unsafe diets may substantially increase the risk of a vicious cycle of enteric infections (EED–environmental enteric dysfunction) and malnutrition (DBM–double burden of malnutrition) in children. Gut melatonin, ma...

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Main Authors: Alane N. Bezerra, Caroline L. Peixoto, Synara C. Lopes, Veralice M. S. Bruin, Pedro Felipe C. Bruin, Reinaldo B. Oriá
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2023.1217173/full
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author Alane N. Bezerra
Alane N. Bezerra
Caroline L. Peixoto
Synara C. Lopes
Veralice M. S. Bruin
Pedro Felipe C. Bruin
Reinaldo B. Oriá
author_facet Alane N. Bezerra
Alane N. Bezerra
Caroline L. Peixoto
Synara C. Lopes
Veralice M. S. Bruin
Pedro Felipe C. Bruin
Reinaldo B. Oriá
author_sort Alane N. Bezerra
collection DOAJ
description Graphical AbstractPoor environmental conditions combined with continuous unhealthy and unsafe diets may substantially increase the risk of a vicious cycle of enteric infections (EED–environmental enteric dysfunction) and malnutrition (DBM–double burden of malnutrition) in children. Gut melatonin, mainly produced by the intestinal microbiota, can modulate the composition, variety, and dynamics of the microbiota itself and may affect and be affected by intestinal microbiota alterations due to DBM and EED.
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spelling doaj.art-4f1a1a7e5b9e44b1b114de50ae3e63f32023-11-27T04:36:56ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-11-011010.3389/fnut.2023.12171731217173The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environmentsAlane N. Bezerra0Alane N. Bezerra1Caroline L. Peixoto2Synara C. Lopes3Veralice M. S. Bruin4Pedro Felipe C. Bruin5Reinaldo B. Oriá6Laboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilLaboratory of Sleep and Biological Rhythms, Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilLaboratory of Sleep and Biological Rhythms, Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilLaboratory of Sleep and Biological Rhythms, Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilLaboratory of Tissue Healing, Ontogeny, and Nutrition, Department of Morphology, Faculty of Medicine, Federal University of Ceará, Fortalez, BrazilGraphical AbstractPoor environmental conditions combined with continuous unhealthy and unsafe diets may substantially increase the risk of a vicious cycle of enteric infections (EED–environmental enteric dysfunction) and malnutrition (DBM–double burden of malnutrition) in children. Gut melatonin, mainly produced by the intestinal microbiota, can modulate the composition, variety, and dynamics of the microbiota itself and may affect and be affected by intestinal microbiota alterations due to DBM and EED. https://www.frontiersin.org/articles/10.3389/fnut.2023.1217173/fullmelatoninthe double burden of malnutritionenvironmental enteric dysfunctionintestinal microbiotapovertyCOVID-19
spellingShingle Alane N. Bezerra
Alane N. Bezerra
Caroline L. Peixoto
Synara C. Lopes
Veralice M. S. Bruin
Pedro Felipe C. Bruin
Reinaldo B. Oriá
The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments
Frontiers in Nutrition
melatonin
the double burden of malnutrition
environmental enteric dysfunction
intestinal microbiota
poverty
COVID-19
title The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments
title_full The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments
title_fullStr The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments
title_full_unstemmed The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments
title_short The double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut-derived melatonin in children under adverse environments
title_sort double burden of malnutrition and environmental enteric dysfunction as potential factors affecting gut derived melatonin in children under adverse environments
topic melatonin
the double burden of malnutrition
environmental enteric dysfunction
intestinal microbiota
poverty
COVID-19
url https://www.frontiersin.org/articles/10.3389/fnut.2023.1217173/full
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