Rationale and design of a multicenter randomized study comparing the efficacy and safety of esaxerenone versus trichlormethiazide in patients with uncontrolled essential hypertension: EXCITE‐HT study

Rationale and design of a multicenter randomized study comparing the efficacy and safety of esaxerenone versus trichlormethiazide in patients with uncontrolled essential hypertension: EXCITE‐HT study

Abstract The next‐generation mineralocorticoid receptor blocker (MRB) esaxerenone has favorable antihypertensive effects in patients who do not respond to treatment with first‐line antihypertensive agents and may be beneficial as a second‐line treatment. However, MRBs are currently considered a four...

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Bibliographic Details
Main Authors: Kazuomi Kario, Mitsuru Ohishi, Tomohiro Katsuya, Takashi Taguchi, Ayumi Tanabe, Kotaro Sugimoto, Tatsuo Shimosawa
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:The Journal of Clinical Hypertension
Subjects:
esaxerenone
hypertension
mineralocorticoid receptor blockers
randomized comparative study
trichlormethiazide
Online Access:https://doi.org/10.1111/jch.14705

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