Cognitive function in female patients with chronic functional constipation
Introduction Chronic functional gastro-intestinal disorders can affect cognitive functioning of patients (1). Wong et al (2) showed attentional and executive function impairment, Aizawa et al. (3) found impairment of cognitive plasticity and activity of frontal and temporal arias of brain during pe...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S092493382200997X/type/journal_article |
| _version_ | 1797617199835250688 |
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| author | M. Morozova G. Rupchev A. Alexeev A. Beniashvili S. Potanin D. Burminskiy T. Lepilkina |
| author_facet | M. Morozova G. Rupchev A. Alexeev A. Beniashvili S. Potanin D. Burminskiy T. Lepilkina |
| author_sort | M. Morozova |
| collection | DOAJ |
| description |
Introduction
Chronic functional gastro-intestinal disorders can affect cognitive functioning of patients (1). Wong et al (2) showed attentional and executive function impairment, Aizawa et al. (3) found impairment of cognitive plasticity and activity of frontal and temporal arias of brain during performing tests in these patients.
Objectives
Assessing of cognitive functioning of the female patients with chronic functional constipation.
Methods
42 Rome IV adult female patients with chronic functional constipation and 26 adult normative female volunteers were tested with Brief Assessment of Cognition in Schizophrenia (BACS).
Results
Both groups were comparable by age (patients’ group 29,5±6,1, volunteers’ group 28,5±9,6, ns) In both groups subjects demonstrated normal level of cognitive functioning but the scores of the patients were closer to the lower level than the scores of the volunteers. The difference was significant in composite scores and in several other scores (Tab.1). Table1.
BACS
Patients (n=42)
Volunteers (n=26)
p-level
Verbal Memory
49,5± 10,6
58,8± 7,1
0,0002
Work memory
48,2±10,1
51,7±8,4
ns
Motor token
51,3±10,5
59,8±10,4
0,003
Verbal fluency
52,1±11,5
56,5±9,9
ns
Symbol coding
45,1±8,4
54,8±12,7
0,015
Tower of London (planning)
50,2±10,7
57,6±10,2
0,015
Composite scores
49,1 ±10,1
59,9 ±7,4
0,0001
Conclusions
The findings of the study once more indicate some link between gastrointestinal dysfunction and cognitive functioning. Even these slight decrease in some aspects of cognition from normal population could have negative impact on everyday functioning. The origin of this link is still under question.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:52:26Z |
| format | Article |
| id | doaj.art-4f1e4139b16e4b0c91b9a776fb1fa707 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:52:26Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-4f1e4139b16e4b0c91b9a776fb1fa7072023-11-17T05:06:25ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S394S39410.1192/j.eurpsy.2022.997Cognitive function in female patients with chronic functional constipationM. Morozova0G. Rupchev1A. Alexeev2A. Beniashvili3S. Potanin4D. Burminskiy5T. Lepilkina6FSBI Research Center of Mental Health, Laboratory Of Psychopharmacology, Moscow, Russian FederationMoscow State University, Faculty Of Psychology, Moscow, Russian FederationFSBI Research Center of Mental Health, Laboratory Of Psychopharmacology, Moscow, Russian FederationFSBI Research Center of Mental Health, Laboratory Of Psychopharmacology, Moscow, Russian FederationFSBI Research Center of Mental Health, Laboratory Of Psychopharmacology, Moscow, Russian FederationFSBI Research Center of Mental Health, Laboratory Of Psychopharmacology, Moscow, Russian FederationFSBI Research Center of Mental Health, Laboratory Of Psychopharmacology, Moscow, Russian Federation Introduction Chronic functional gastro-intestinal disorders can affect cognitive functioning of patients (1). Wong et al (2) showed attentional and executive function impairment, Aizawa et al. (3) found impairment of cognitive plasticity and activity of frontal and temporal arias of brain during performing tests in these patients. Objectives Assessing of cognitive functioning of the female patients with chronic functional constipation. Methods 42 Rome IV adult female patients with chronic functional constipation and 26 adult normative female volunteers were tested with Brief Assessment of Cognition in Schizophrenia (BACS). Results Both groups were comparable by age (patients’ group 29,5±6,1, volunteers’ group 28,5±9,6, ns) In both groups subjects demonstrated normal level of cognitive functioning but the scores of the patients were closer to the lower level than the scores of the volunteers. The difference was significant in composite scores and in several other scores (Tab.1). Table1. BACS Patients (n=42) Volunteers (n=26) p-level Verbal Memory 49,5± 10,6 58,8± 7,1 0,0002 Work memory 48,2±10,1 51,7±8,4 ns Motor token 51,3±10,5 59,8±10,4 0,003 Verbal fluency 52,1±11,5 56,5±9,9 ns Symbol coding 45,1±8,4 54,8±12,7 0,015 Tower of London (planning) 50,2±10,7 57,6±10,2 0,015 Composite scores 49,1 ±10,1 59,9 ±7,4 0,0001 Conclusions The findings of the study once more indicate some link between gastrointestinal dysfunction and cognitive functioning. Even these slight decrease in some aspects of cognition from normal population could have negative impact on everyday functioning. The origin of this link is still under question. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S092493382200997X/type/journal_articlechronic functional constipationfemalecognitive function |
| spellingShingle | M. Morozova G. Rupchev A. Alexeev A. Beniashvili S. Potanin D. Burminskiy T. Lepilkina Cognitive function in female patients with chronic functional constipation European Psychiatry chronic functional constipation female cognitive function |
| title | Cognitive function in female patients with chronic functional constipation |
| title_full | Cognitive function in female patients with chronic functional constipation |
| title_fullStr | Cognitive function in female patients with chronic functional constipation |
| title_full_unstemmed | Cognitive function in female patients with chronic functional constipation |
| title_short | Cognitive function in female patients with chronic functional constipation |
| title_sort | cognitive function in female patients with chronic functional constipation |
| topic | chronic functional constipation female cognitive function |
| url | https://www.cambridge.org/core/product/identifier/S092493382200997X/type/journal_article |
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