A paradoxical switch: the implications of excitatory GABAergic signaling in neurological disorders

A paradoxical switch: the implications of excitatory GABAergic signaling in neurological disorders

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. In the mature brain, inhibitory GABAergic signaling is critical in maintaining neuronal homeostasis and vital human behaviors such as cognition, emotion, and motivation. While classically known t...

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Bibliographic Details
Main Authors: Colin J. McArdle, Alana A. Arnone, Chelcie F. Heaney, Kimberly F. Raab-Graham
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Psychiatry
Subjects:
GABA
depolarizing
excitatory
diseases
GABAARs
neurological
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1296527/full

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