Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management
Vipul D Yagnik,1 Sushil Dawka,2 Nitin Patel3 1Department of Surgical Gastroenterology, Nishtha Surgical Hospital and Research Centre, Patan, Gujarat, India; 2Department of Surgery, SSR Medical College, Belle Rive, Mauritius; 3Department of Surgical Gastroenterology, Gujarat Superspeciality Hospital,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-04-01
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| Series: | Clinical and Experimental Gastroenterology |
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| Online Access: | https://www.dovepress.com/gallbladder-hydatid-cyst-a-review-on-clinical-features-investigations--peer-reviewed-article-CEG |
| _version_ | 1818198664709931008 |
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| author | Yagnik VD Dawka S Patel N |
| author_facet | Yagnik VD Dawka S Patel N |
| author_sort | Yagnik VD |
| collection | DOAJ |
| description | Vipul D Yagnik,1 Sushil Dawka,2 Nitin Patel3 1Department of Surgical Gastroenterology, Nishtha Surgical Hospital and Research Centre, Patan, Gujarat, India; 2Department of Surgery, SSR Medical College, Belle Rive, Mauritius; 3Department of Surgical Gastroenterology, Gujarat Superspeciality Hospital, Baroda, Gujarat, IndiaCorrespondence: Vipul D YagnikDepartment of Surgical Gastroenterology, Nishtha Surgical Hospital and Research Centre, Patan, Gujarat 384265, IndiaEmail vipul.yagnik@gmail.comBackground: Gallbladder hydatid cyst (GBHC) is highly uncommon with an incidence of 0.3– 0.4% of all atypically located hydatid cysts. Our personal experience of one case of primary GBHC (PGBHC) managed laparoscopically motivated this systematic review. This study aimed to analyze the demographic characteristics, types [whether primary GBHC (PGBHC) or secondary GBHC (SGBHC)], clinical presentation, laboratory investigations, imaging studies, operative procedure, hospital stay, follow-up and recurrence.Methods: A systematic review was performed using preferred reporting items for systematic reviews and meta-analyses guidelines.Results: Twenty studies, including 22 cases plus one more case managed by us, were included in the review. For PGBHC, the mean age was 48.61 years while for SGBHC it was 47.9 years. PGBHC was more common in females (69.23%) while SGBHC was more common in males (55.55%). Overall, GBHC was more common in females (56.52%). The most common presentation overall was abdominal pain (100%) followed by nausea/vomiting (43.47%). The other common symptoms were nausea/vomiting (61.53%) and Murphy’s sign (38.46%) in PGBHC, but jaundice (50%) and fever (30%) in SGBHC. In PGBHC, 50% patients had normal liver function while this was deranged in 66.66% patients with SGBHC. Serology was positive in 50% of PGBHC and 100% in SGBHC. Ultrasonography was positive in 50%, while CT-scan showed 70%. CT-scan was better at detection of SGBHC (100%). The most common operation was open cholecystectomy (78.26%) either isolated or combined. Isolated open cholecystectomy was commonly done in PGBHC (69.23%). Overall, only 56.52% of patients received albendazole, but no recurrence was reported. The average hospital stay was 7.25 days and follow-up ranged from 1 month to 10 years.Conclusion: GBHC mostly affects females with abdominal pain being the most common symptom. Ultrasonography is expedient though CT-scan is more sensitive. Albendazole monotherapy has questionable value. Open cholecystectomy is the most common operation. However, laparoscopy is safe in experienced hands.Keywords: hydatid, cyst, gallbladder, primary, secondary |
| first_indexed | 2024-12-12T02:09:28Z |
| format | Article |
| id | doaj.art-4f2724af98d44fe993e56ed7d0f112fe |
| institution | Directory Open Access Journal |
| issn | 1178-7023 |
| language | English |
| last_indexed | 2024-12-12T02:09:28Z |
| publishDate | 2020-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical and Experimental Gastroenterology |
| spelling | doaj.art-4f2724af98d44fe993e56ed7d0f112fe2022-12-22T00:41:57ZengDove Medical PressClinical and Experimental Gastroenterology1178-70232020-04-01Volume 13879752896Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current ManagementYagnik VDDawka SPatel NVipul D Yagnik,1 Sushil Dawka,2 Nitin Patel3 1Department of Surgical Gastroenterology, Nishtha Surgical Hospital and Research Centre, Patan, Gujarat, India; 2Department of Surgery, SSR Medical College, Belle Rive, Mauritius; 3Department of Surgical Gastroenterology, Gujarat Superspeciality Hospital, Baroda, Gujarat, IndiaCorrespondence: Vipul D YagnikDepartment of Surgical Gastroenterology, Nishtha Surgical Hospital and Research Centre, Patan, Gujarat 384265, IndiaEmail vipul.yagnik@gmail.comBackground: Gallbladder hydatid cyst (GBHC) is highly uncommon with an incidence of 0.3– 0.4% of all atypically located hydatid cysts. Our personal experience of one case of primary GBHC (PGBHC) managed laparoscopically motivated this systematic review. This study aimed to analyze the demographic characteristics, types [whether primary GBHC (PGBHC) or secondary GBHC (SGBHC)], clinical presentation, laboratory investigations, imaging studies, operative procedure, hospital stay, follow-up and recurrence.Methods: A systematic review was performed using preferred reporting items for systematic reviews and meta-analyses guidelines.Results: Twenty studies, including 22 cases plus one more case managed by us, were included in the review. For PGBHC, the mean age was 48.61 years while for SGBHC it was 47.9 years. PGBHC was more common in females (69.23%) while SGBHC was more common in males (55.55%). Overall, GBHC was more common in females (56.52%). The most common presentation overall was abdominal pain (100%) followed by nausea/vomiting (43.47%). The other common symptoms were nausea/vomiting (61.53%) and Murphy’s sign (38.46%) in PGBHC, but jaundice (50%) and fever (30%) in SGBHC. In PGBHC, 50% patients had normal liver function while this was deranged in 66.66% patients with SGBHC. Serology was positive in 50% of PGBHC and 100% in SGBHC. Ultrasonography was positive in 50%, while CT-scan showed 70%. CT-scan was better at detection of SGBHC (100%). The most common operation was open cholecystectomy (78.26%) either isolated or combined. Isolated open cholecystectomy was commonly done in PGBHC (69.23%). Overall, only 56.52% of patients received albendazole, but no recurrence was reported. The average hospital stay was 7.25 days and follow-up ranged from 1 month to 10 years.Conclusion: GBHC mostly affects females with abdominal pain being the most common symptom. Ultrasonography is expedient though CT-scan is more sensitive. Albendazole monotherapy has questionable value. Open cholecystectomy is the most common operation. However, laparoscopy is safe in experienced hands.Keywords: hydatid, cyst, gallbladder, primary, secondaryhttps://www.dovepress.com/gallbladder-hydatid-cyst-a-review-on-clinical-features-investigations--peer-reviewed-article-CEGhydatidcystgallbladderprimarysecondary |
| spellingShingle | Yagnik VD Dawka S Patel N Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management Clinical and Experimental Gastroenterology hydatid cyst gallbladder primary secondary |
| title | Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management |
| title_full | Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management |
| title_fullStr | Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management |
| title_full_unstemmed | Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management |
| title_short | Gallbladder Hydatid Cyst: A Review on Clinical Features, Investigations and Current Management |
| title_sort | gallbladder hydatid cyst a review on clinical features investigations and current management |
| topic | hydatid cyst gallbladder primary secondary |
| url | https://www.dovepress.com/gallbladder-hydatid-cyst-a-review-on-clinical-features-investigations--peer-reviewed-article-CEG |
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