Effects of TRPC6 Inactivation on Glomerulosclerosis and Renal Fibrosis in Aging Rats
Canonical transient receptor potential 6 (TRPC6) channels have been implicated in familial and acquired forms of focal and segmental glomerulosclerosis (FSGS) in patients and animal models, as well as in renal fibrosis following ureteral obstruction in mice. Aging also evokes declines in renal funct...
Main Authors: | Eun Young Kim, Stuart E. Dryer |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/4/856 |
Similar Items
-
TRPC6 Inactivation Reduces Albuminuria Induced by Protein Overload in Sprague Dawley Rats
by: Eun Young Kim, et al.
Published: (2022-06-01) -
ATRA attenuate proteinuria via downregulation of TRPC6 in glomerulosclerosis rats induced by adriamycin
by: Lei Zhang, et al.
Published: (2018-10-01) -
The Effects of TRPC6 Knockout in Animal Models of Kidney Disease
by: Stuart E. Dryer, et al.
Published: (2022-11-01) -
TRPC6 Inhibitor BI 764198 in Focal Segmental Glomerulosclerosis: Phase 2 Study Design
by: Howard Trachtman, et al.
Published: (2023-12-01) -
20-Hydroxyeicosatetraenoic acid (20-HETE) Modulates Canonical Transient Receptor Potential-6 (TRPC6) Channels in Podocytes
by: Hila Roshanravan, et al.
Published: (2016-08-01)