Are Antibiotics Needed for Common Throat Infections?
Objective Ever fuelling antibiotic use and resulting resistance is still prevalent in our society most commonly prescribed for throat infections. However community acquired throat infections are known to be caused mostly by viruses, therefore it was of interest to determine the incidence of bacter...
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| Format: | Article |
| Language: | English |
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Dow University of Health Sciences
2012-06-01
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| Series: | Journal of the Dow University of Health Sciences |
| Subjects: | |
| Online Access: | https://jduhs.com/index.php/jduhs/article/view/1498 |
| _version_ | 1797818425331941376 |
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| author | Farhan Essaa Abdullah Atif Rasool Hafiz Muazzam Ali Fahad Shamsi Wardah Muazzam |
| author_facet | Farhan Essaa Abdullah Atif Rasool Hafiz Muazzam Ali Fahad Shamsi Wardah Muazzam |
| author_sort | Farhan Essaa Abdullah |
| collection | DOAJ |
| description | Objective
Ever fuelling antibiotic use and resulting resistance is still prevalent in our society most commonly prescribed for throat infections. However community acquired throat infections are known to be caused mostly by viruses, therefore it was of interest to determine the incidence of bacterial species grown from infected throats and whether the character of these isolates indicated antibiotic intervention to control ever increasing antibiotic resistances.
Design
Prospective Study.
Place and Duration
At a private Lab and Diagnostic Centre, Karachi, Pakistan during Jan 2010 to July 2011.
Method
The isolates from 362 patients of all ages presenting with RTI were cultured and identified using standard protocol. Antibiotic sensitivity of these isolates was checked using 23 drugs and the Kirby-Bauer disc diffusion method at a private lab in Karachi. In addition, to know the perspective of ENT specialists regarding the antibiotic resistance, rate of their prescriptions and the drugs they prescribe, 30 questionnaires were also collected.
Results
Among the 362 isolates Pneumococci were most commonly seen (35.34%) followed by Staphylococcus aureus (23.01%) and notable Klebsiella pneumoniae (14.5%). The ENT physicians interviewed commonly prescribed any of 20 antibiotics, most often Amoxicillin, Amoxiclav or even the injectables Cefotaxime, Ceftriaxone for pharyngitis. In our study, among others, the isolates were most sensitive to Cefotaxime (91.2%),
Conclusion
Pneumococci and Staphylococci were most often isolated from infected throats; these were likely part of residential flora accompanying infecting respiratory viruses, the drug therapy was hence superfluous and essentially harmful.
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| first_indexed | 2024-03-13T09:07:46Z |
| format | Article |
| id | doaj.art-4f2c7f7082a6493e9dab033c1afdd62a |
| institution | Directory Open Access Journal |
| issn | 1995-2198 2410-2180 |
| language | English |
| last_indexed | 2024-03-13T09:07:46Z |
| publishDate | 2012-06-01 |
| publisher | Dow University of Health Sciences |
| record_format | Article |
| series | Journal of the Dow University of Health Sciences |
| spelling | doaj.art-4f2c7f7082a6493e9dab033c1afdd62a2023-05-28T03:11:19ZengDow University of Health SciencesJournal of the Dow University of Health Sciences1995-21982410-21802012-06-0162Are Antibiotics Needed for Common Throat Infections?Farhan Essaa Abdullah0Atif Rasool1Hafiz Muazzam Ali2Fahad Shamsi3Wardah Muazzam4Dr. Essa’s Laboratory and Diagnostic Centre, Karachi, PakistanUndergraduate MBBS Student, Sndh Medical College, Dow University of Health Sciences, Karachi, Pakistan.Undergraduate MBBS Student, Dow Medical College, Dow University of Health Sciences, Karachi, PakistanUndergraduate MBBS Student, Dow Medical College, Dow University of Health Sciences, Karachi, PakistanUndergraduate MBBS Student, Dow Medical College, Dow University of Health Sciences, Karachi, PakistanObjective Ever fuelling antibiotic use and resulting resistance is still prevalent in our society most commonly prescribed for throat infections. However community acquired throat infections are known to be caused mostly by viruses, therefore it was of interest to determine the incidence of bacterial species grown from infected throats and whether the character of these isolates indicated antibiotic intervention to control ever increasing antibiotic resistances. Design Prospective Study. Place and Duration At a private Lab and Diagnostic Centre, Karachi, Pakistan during Jan 2010 to July 2011. Method The isolates from 362 patients of all ages presenting with RTI were cultured and identified using standard protocol. Antibiotic sensitivity of these isolates was checked using 23 drugs and the Kirby-Bauer disc diffusion method at a private lab in Karachi. In addition, to know the perspective of ENT specialists regarding the antibiotic resistance, rate of their prescriptions and the drugs they prescribe, 30 questionnaires were also collected. Results Among the 362 isolates Pneumococci were most commonly seen (35.34%) followed by Staphylococcus aureus (23.01%) and notable Klebsiella pneumoniae (14.5%). The ENT physicians interviewed commonly prescribed any of 20 antibiotics, most often Amoxicillin, Amoxiclav or even the injectables Cefotaxime, Ceftriaxone for pharyngitis. In our study, among others, the isolates were most sensitive to Cefotaxime (91.2%), Conclusion Pneumococci and Staphylococci were most often isolated from infected throats; these were likely part of residential flora accompanying infecting respiratory viruses, the drug therapy was hence superfluous and essentially harmful. https://jduhs.com/index.php/jduhs/article/view/1498PharyngitisTonsillitisIsolatesAntibioticsResistance |
| spellingShingle | Farhan Essaa Abdullah Atif Rasool Hafiz Muazzam Ali Fahad Shamsi Wardah Muazzam Are Antibiotics Needed for Common Throat Infections? Journal of the Dow University of Health Sciences Pharyngitis Tonsillitis Isolates Antibiotics Resistance |
| title | Are Antibiotics Needed for Common Throat Infections? |
| title_full | Are Antibiotics Needed for Common Throat Infections? |
| title_fullStr | Are Antibiotics Needed for Common Throat Infections? |
| title_full_unstemmed | Are Antibiotics Needed for Common Throat Infections? |
| title_short | Are Antibiotics Needed for Common Throat Infections? |
| title_sort | are antibiotics needed for common throat infections |
| topic | Pharyngitis Tonsillitis Isolates Antibiotics Resistance |
| url | https://jduhs.com/index.php/jduhs/article/view/1498 |
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