Quercetin’s Dual Mode of Action to Counteract the Sp1-miR-27a Axis in Colorectal Cancer Cells

Quercetin’s Dual Mode of Action to Counteract the Sp1-miR-27a Axis in Colorectal Cancer Cells

Quercetin (Qc) inhibits cell proliferation and induces apoptosis in a variety of cancer cells. The molecular mechanism of action has not been fully elucidated; however, interplay with some miRNAs has been reported, specifically with miR-27a, an onco-miRNA overexpressed in several malignancies. Here,...

Full description

Bibliographic Details
Main Authors: Emanuele Fosso, Manuela Leo, Livio Muccillo, Vittorio Maria Mandrone, Maria Chiara Di Meo, Annamaria Molinario, Ettore Varricchio, Lina Sabatino
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Antioxidants
Subjects:
quercetin
colorectal cancer cells
miRNAs
miR-27a
miR-23a
miR-24-2
Online Access:https://www.mdpi.com/2076-3921/12/8/1547

Similar Items

Similar Items